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Buccal Misoprostol During Cesarean Section for Preventing Postpartum Hemorrhage

Postpartum Hemorrhage Clinical Trial

Official title:
Buccal Misoprostol During Cesarean Section for Preventing Postpartum Hemorrhage in Women With Risk Factors for Uterine Atony

Clinical Trial Summary

Objective: to demonstrate that buccal misoprostol administration during cesarean delivery in women with risk factors for uterine atony decreases the need for additional uterotonic medications, uterine atony and postpartum hemorrhage.

Design: randomized, double-blinded, placebo-controlled trial.

Clinical Trial Description

Patients and methods: 120 pregnant women with risk factors for uterine atony who underwent cesarean delivery were assigned randomly to either 400 mcg misoprostol (n=60) or placebo (n=60) placed in buccal space after umbilical cord clamping. The primary outcome variables were the need for additional uterotonic agents, estimated blood loss and uterine atony. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01733329
Study type Interventional
Source Hospital Universitario Dr. Jose E. Gonzalez
Contact
Status Completed
Phase Phase 4
Start date February 2008
Completion date December 2013
View Details
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