Ultrasound-Guided Internal Superior Laryngeal Nerve Block for Double-Lumen Bronchial Tube

Postoperative Sore Throat Clinical Trial

Official title:

Effect of Ultrasound-Guided Internal Superior Laryngeal Nerve Block on Sore Throat After Intubation by Double-Lumen Bronchial Tube for Thoracoscopic Surgery

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05825872
• Other study ID #: 2/2023ANET15-1
• Status: Recruiting
• Phase: Phase 4
• Start date: April 5, 2023
• Est. completion date: September 5, 2023

Study information

• Verified date: April 2023
• Source: Menoufia University
• Contact: mostafa S mansour, MD
• Phone: 00201225484055
• Email: mostafa.said[@]med.menofia.edu.eg
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

investigate the effectiveness and safety of ultrasound-guided bilateral internal branch of the SLN (iSLN) block for alleviating POST immediately after the operation.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 64
• Est. completion date: September 5, 2023
• Est. primary completion date: July 5, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 75 Years

Eligibility

Inclusion Criteria:

• ASA 1 to 3

Exclusion Criteria:

• patients who did not provide consent
• with a pre-existing sore throat, hoarseness and upper respiratory tract infection
• tracheal pathology, tracheostomy
• a history of psychosis, diabetes and thyroid, oral cavity or pharynx surgery
• known or suspected allergy to ropivacaine
• chronic opioid use
• use of nonsteroidal anti-inflammatory drug medication within 24 hours
• known or suspected difficult airway
• patients who will be supported by tube ventilator after the operation.

Related Conditions & MeSH terms

• Pharyngitis
• Postoperative Sore Throat

Intervention

Procedure:
• internal superior laryngeal nerve block
A linear 4- to 12-MHz ultrasound probe will be placed in the oblique parasagittal plane to obtain an image of the hyoid bone and the thyroid cartilage. The probe will be kept parasagitally, and the following structures will be identified anteriorly to posteriorly: omohyoid muscle, sternohyoid muscle, thyrohyoid muscle, thyrohyoid membrane, superior laryngeal artery, and pre-epiglottis space. After identifying the local anatomic structure, a needle will be inserted out-plane from anterior to posterior. The muscles above the thyrohyoid membrane will be penetrated and hydrodissected; local anesthetic will be injected into the superior laryngeal nerve space. The superior laryngeal nerve space will be located between the hyoid bone (cephalad) and the thyroid cartilage (caudal) and delimited between the thyrohyoid muscle, anteriorly, and the thyrohyoid membrane and the pre-epiglottis space, posteriorly

Drug:
• Lidocaine 2% Injectable Solution
0.5 ml will be injected
• Bupivacaine 0.5% Injectable Solution
1.5 ml will be injected

Locations

Country	Name	City	State
Egypt	Menoufia University Hospitals	Shibin Al Kawm	Menoufia

Sponsors (1)

Lead Sponsor	Collaborator
Menoufia University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	the pain classification of postoperative sore throat	an established scoring system feom 0 to 4	from immediate postoperative till 24 hours postoperative