Efficacy of K-Y Jelly in Prevention of Postoperative Sore Throat After Nasal Surgery

Postoperative Sore Throat Clinical Trial

Official title:

Efficacy of K-Y Jelly in Prevention of Postoperative Sore Throat After Nasal Surgery

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05436743
• Other study ID #: 072021
• Status: Recruiting
• Phase: Phase 4
• Start date: July 1, 2022
• Est. completion date: August 2022

Study information

• Verified date: June 2022
• Source: Egyptian Biomedical Research Network
• Contact: Ahmed Algarhy, PhD
• Phone: 0 111 088 8332
• Email: Elgarhy_79[@]yahoo.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Postoperative sore throat (POST) is a fairly common side effect of general anesthesia which is caused by the mucosal injury and nerve compression associated with tracheal intubation or laryngeal mask airway device insertion. In this randomized study, the authors evaluate the effect of K-Y jelly-soaked nasopharyngeal packs on POST and postoperative nausea and vomiting in patients subjected to nasal surgery.

Description:

Postoperative sore throat (POST) is a fairly common side effect of general anesthesia which is caused by the mucosal injury and nerve compression associated with tracheal intubation or laryngeal mask airway device insertion. In this randomized study, the authors evaluate the effect of K-Y jelly-soaked nasopharyngeal packs on POST and postoperative nausea and vomiting in patients subjected to nasal surgery. The present double-blinded randomized controlled study was conducted at Al-Azhar University Hospitals, Cairo, Egypt. The study protocol was approved by the local ethical committee of Al-Azhar Faculty of Medicine and all patients provided informed consent before enrollment in the study.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 140
• Est. completion date: August 2022
• Est. primary completion date: August 1, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patients submitted to nasal surgery under general anesthesia.

Exclusion Criteria:

• Acute of chronic nasopharyngeal conditions,
• Gastroesophageal reflux, regurgitation,
• History of postoperative sore throat,
• nasal surgery for malignant disease,
• concurrent or recent use of systemic or topical agents used for sore throat or
• Mallampati grade more than 2.

Related Conditions & MeSH terms

• Pharyngitis
• Postoperative Sore Throat

Intervention

Drug:
• K-Y Jelly, Topical Gel soaked packs
Topical Gel used as lubricant

Other:
• Water soaked packs
Water soaked packs for reduction of postoperative sore throat

Locations

Country	Name	City	State
Egypt	Al-Azhar University Hospitals	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Alaa Gamal

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Postoperative sore throat	Postoperative sore throat	up to 6 hours postoperatively