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Clinical Trial Details — Status: Enrolling by invitation

Administrative data

NCT number NCT04644900
Other study ID # Na Chen
Secondary ID
Status Enrolling by invitation
Phase N/A
First received
Last updated
Start date December 31, 2020
Est. completion date December 31, 2021

Study information

Verified date November 2020
Source Fudan University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Postoperative sore throat (POST) is an important problem after general anaesthesia. We assessed whether chewing gum preoperatively or mouthwash can reduce the incidence of POST after general anaesthesia administered via a streamlined liner of the pharyngeal airway (SLIPA).


Recruitment information / eligibility

Status Enrolling by invitation
Enrollment 70
Est. completion date December 31, 2021
Est. primary completion date December 31, 2021
Accepts healthy volunteers No
Gender Female
Age group 20 Years to 65 Years
Eligibility Inclusion Criteria: American Society of Anaesthesiologists(ASA)class I or II 20~65 years body mass index(BMI)scores<30 undergoing elective hysteroscopic surgery Exclusion Criteria: chronic laryngitis chronic bronchitis asthma gastroesophageal reflux allergies to study drugs recent use of non-steroidal anti-inflammatory drugs(NSAIDS) a history of upper respiratory tract infection in the past one week Mallampati grade>2 a history of steroid therapy.

Study Design


Related Conditions & MeSH terms


Intervention

Other:
chewed mint gum
In the preoperative waiting area before transferring to the operating room,patients in group G chewed mint gum for 2 minutes and then spit it out.
Mouthwash
Patients in the mouthwash group took 15 ml honeysuckle antibacterial mouthwash in their mouths, and vomited them out after 2 minutes

Locations

Country Name City State
China Ethics Committee of The Obstetrics and Gynecology Hospital, Fudan University, Shanghai

Sponsors (1)

Lead Sponsor Collaborator
Fudan University

Country where clinical trial is conducted

China, 

Outcome

Type Measure Description Time frame Safety issue
Other subgroup analysis with patient subdivided based on whether the laryngeal mask had blood on it. blood stain Immediately after removal of laryngeal mask
Primary the incidence of POST scores>3 POST was evaluated by the Numerical Rating Scale(NRS),which ranges from 0 to 10 points,with 0 indicating completely painless,1~3 indicating mild discomfort,4~6 indicating moderate pain,and 7~10 indicating severe pain . within 24 hours after surgery.
Secondary the POST scores POST was evaluated by the Numerical Rating Scale(NRS),which ranges from 0 to 10 points,with 0 indicating completely painless,1~3 indicating mild discomfort,4~6 indicating moderate pain,and 7~10 indicating severe pain . 2 hours,6 hours and 24 hours after surgery.
See also
  Status Clinical Trial Phase
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Recruiting NCT06266481 - Topical Dexamethasone Versus Topical Lidocaine Spray to Reduce POST in Shoulder Arthroscopic Surgeries: A Comparative Study Phase 2/Phase 3
Recruiting NCT05436743 - Efficacy of K-Y Jelly in Prevention of Postoperative Sore Throat After Nasal Surgery Phase 4
Recruiting NCT06218836 - Effect of Inflated Versus Non-inflated Endotracheal Tube on Sore Throat N/A
Not yet recruiting NCT03792776 - Effect of Lidocaine 1% and 2% in the Tube Cuff on Postoperative Sore Throat and Cough N/A
Completed NCT04371094 - Sore Throat After Intubation Using Glidescope With Stylet and Bougie N/A
Active, not recruiting NCT06122324 - Effect of Lidocaine on Hemodynamic Response and Postoperative Sore Throat
Completed NCT02492646 - Effect of Saline Lubrication on Post-intubation Complications N/A
Recruiting NCT05825872 - Ultrasound-Guided Internal Superior Laryngeal Nerve Block for Double-Lumen Bronchial Tube Phase 4
Not yet recruiting NCT06368843 - the Impact of Ketamine Gargling on the Incidence of Post Intubation Sore Throat