Postoperative Sedation Clinical Trial
Official title:
Target-controlled Infusion of Propofol and Remifentanil for Postoperative Sedation Guided by the Bispectral Index: Comparison Between Manual Perfusion and Automated Perfusion
This prospective randomized study evaluates the effectiveness of a closed-loop anesthesia system during the postoperative period.
Status | Completed |
Enrollment | 32 |
Est. completion date | April 2007 |
Est. primary completion date | April 2007 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - American Society of Anesthesiologists physical status 1-3 - Abdominal aorta surgery Exclusion Criteria: - Pregnant women - Neurological or muscular disorder |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
France | Dept of Anesthesia and Intensive Care, Hopital Pitié-Salpêtrière | Paris | |
France | Hôpital Foch | Suresnes |
Lead Sponsor | Collaborator |
---|---|
Hopital Foch |
France,
Liu N, Chazot T, Genty A, Landais A, Restoux A, McGee K, Laloë PA, Trillat B, Barvais L, Fischler M. Titration of propofol for anesthetic induction and maintenance guided by the bispectral index: closed-loop versus manual control: a prospective, randomized, multicenter study. Anesthesiology. 2006 Apr;104(4):686-95. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Global score (calculated parameter which depicts the performance of the system) | |||
Secondary | Consumption of propofol and remifentanil, modifications of target of propofol and remifentanil, dysfunction of each system, hemodynamic abnormalities, sedation scale, volume loading, extubation time, explicit memorisation. |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT00125398 -
GPI 15715 For Sedation in the Intensive Care Unit (ICU) Setting
|
Phase 2 | |
Completed |
NCT01507363 -
Analgesic Effect of Gabapentin in Total Knee Arthroplasty (TKA)
|
Phase 4 | |
Completed |
NCT03723538 -
Dexmedetomidine Use for Sedation in Patients Submitted to Tracheal Surgery
|