Impact of Postoperative Transitional Pain on Recovery After Thoracic Surgery

Postoperative Recovery Clinical Trial

— TRANSAT  

Official title:

Impact of Postoperative Transitional Pain on Recovery After Thoracic Surgery

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05450172
• Other study ID #: 49RC22_0203
• Status: Not yet recruiting
• Start date: September 20, 2022
• Est. completion date: January 6, 2025

Study information

• Verified date: July 2022
• Source: University Hospital, Angers
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Postoperative transitional pain corresponds to the pain occuring between acute postoperative pain and chronic postsurgical pain (defined as pain persisting for at least 3 months after surgery). We hypothesized that both trajectory and neuropathic component of transitional pain may influence the quality of recovery after thoracic surgery. To test this, we designed an observational study to identify risk factors for incomplete recovery assessed through the QoR-15 questionnaire.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 200
• Est. completion date: January 6, 2025
• Est. primary completion date: October 3, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• adult patients
• patients scheduled for thoracic surgery (thoracotomy or video-assisted thoracic surgery or surgery for thoracic outlet syndrome)
• patients who do not object to the study

Exclusion Criteria:

• patients non francophone
• emergency surgery or revision surgery
• patients already included in the study during the previous 6 months

Related Conditions & MeSH terms

• Postoperative Recovery

Intervention

Other:
• QoR-15 questionnaire
The QoR-15 is a 15-item questionnaire on postoperative quality of recovery. The DN4 is a 10-item questionnaire on neuropathic pain. Both questionnaires will be given to the patients preoperatively, on postoperative days 2 and 3, and 1, 3 and 6 months after surgery.

Locations

Country	Name	City	State
France	CHU	Angers

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Angers

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Impact of pain trajectory and neuropathic component of pain on quality of recovery.	An incomplete recovery will be defined as a postoperative QoR-15 score of at least 8 points lower than the preoperative QoR-15 value. The association between both trajectory and neuropathic component of postoperative transitional pain and incomplete recovery will be evaluated.	3 months after surgery.
Secondary	Description of trajectory and neuropathic component of postoperative transitional pain.	To describe the trajectory and neuropathic component of postoperative transitional pain according to QoR-15 and DN4 successive values.	Between postoperative day 2 and 3 months after surgery.
Secondary	Impact of the type of surgery on quality of recovery.	To assess the impact of thoracotomy or video-assisted thoracic on quality of recovery.	3 months after surgery.
Secondary	Impact of pain trajectory, neuropathic component of pain and type of surgery on chronic postsurgical pain prevalence.	To assess the impact pain trajectory, neuropathic component of pain and type of surgery on chronic postsurgical pain prevalence.	3 and 6 months after surgery.
Secondary	Predictive accuracy of neuropathic pain trajectory on incomplete recovery and chronic postsurgical pain prevalence.	To assess the predictive accuracy of neuropathic pain trajectory on incomplete recovery and chronic postsurgical pain prevalence.	3 and 6 months after surgery.
Secondary	Correlation between neuropathic componente of chronic postsurgical pain and quality of recovery.	To assess the correlation between neuropathic componente of chronic postsurgical pain and quality of recovery.	3 and 6 months after surgery.