Efficacy of Serratus Anterior Plane Block Mastectomy

Postoperative Pain Clinical Trial

Official title:

Efficacy of Serratus Anterior Plane Block Using Bupivacaine/Magnesium Sulphate Versus Bupivacaine/Nalbuphine for Mastectomy: a Randomized Double Blinded Comparative Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03944759
• Other study ID #: FMBSURECS/30042019/Ali
• Status: Completed
• Phase: N/A
• Start date: May 7, 2019
• Est. completion date: December 1, 2019

Study information

• Verified date: February 2020
• Source: Beni-Suef University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Breast cancer is the main common cancer among females. . Inadequate control of pain may later develop into chronic pain syndrome (paraesthesias, phantom breast pain, and intercostobrachial neuralgia) in 25-40% of the patients .

Description:

The aim of this study is to compare the efficacy of ultrasound-guided serratus anterior plane block with bupivacaine/ magnesium versus bupivacaine/ nalbuphine in breast cancer surgery.

Patients and methods nclusion criteria:

-ASA I and II female patients, age 25-60 undergoing breast cancer surgery

Exclusion criteria:

• Patient refusal

• Contraindications for regional blocks (eg. Infection at the injection site, coagulopathy)

• Allergy to the drugs used in the study

• Chronic pain therapy,

• BMI more than 30 kg/m2

Recruitment information / eligibility

• Status: Completed
• Enrollment: 40
• Est. completion date: December 1, 2019
• Est. primary completion date: December 1, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 25 Years to 60 Years

Eligibility

Inclusion Criteria:

• ASA I and II female patients, age 25-60 undergoing breast cancer surgery

Exclusion Criteria:

• -Patient refusal

• Contraindications for regional blocks (eg. Infection at the injection site, coagulopathy)

• Allergy to the drugs used in the study

• Chronic pain therapy,

• BMI more than 30 kg/m2

Related Conditions & MeSH terms

• Postoperative Complications
• Postoperative Pain

Intervention

Procedure:
• serratus anterior plan block
serratus anterior plan block

Locations

Country	Name	City	State
Egypt	Faculty Of Medicine, Beni-Suef University	Bani Suwayf

Sponsors (1)

Lead Sponsor	Collaborator
doaa rashwan

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	time to first analgesic requirements in minutes	time to first analgesic requirements in minutes by the patient	change from base line for 24 hours