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Postoperative Pain clinical trials

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NCT ID: NCT06187922 Recruiting - Postoperative Pain Clinical Trials

Effect of Perioperative Oral Pregabalin in Total Knee Replacement

TKR
Start date: September 1, 2023
Phase: Phase 4
Study type: Interventional

This interventional randomized control trial aim to determine efficacy and safety of Oral pregabalin in improving after surgery pain control in patients undergoing total knee replacement surgeries under regional anesthesia. We'll compare the efficacy of pregabalin between two groups, pregabalin group and control group on the basis of their opioid consumption after knee operation.

NCT ID: NCT06187688 Not yet recruiting - Postoperative Pain Clinical Trials

Measuring Pain Intensity in Cesarean Patients

Start date: January 2024
Phase:
Study type: Observational

Pain intensity is commonly measured in research and clinical settings. Primary objective: To evaluate psychometric properties (validity, reliability, and utility) of 5 pain measurement tools: a verbal 11-point NRS, the FPS-R, a 6-point VDS, an 11-point NRS, and a 100 mm VAS in a sample of cesarean section patients. Secondary objectives: To evaluate whether the (new) word "very severe pain" is easier for patients to understand in comparison to the (old) word "worst pain imaginable. To evaluate whether the (new) word "overall pain" is easier for patients to understand in comparison to the (old) word "average pain".

NCT ID: NCT06183073 Recruiting - Postoperative Pain Clinical Trials

Caudal Block With Bupivacaine and Dexmedetomidine Versus TAP Block With Bupivacaine Alone for Postoperative Analgesia in Pediatric Undergoing Infraumbical Surgeries

Start date: April 2, 2023
Phase: Phase 2
Study type: Interventional

Acute pain management for pediatric surgical patients intraoperatively and postoperatively is important for their comfort and psychological impact. Children aged 3-9 years old are included in the study and are divided randomly into two groups (45 children in each): Group D: Caudal block with bupivacaine 0.25% in a dose of (1 ml / kg) and dexmedetomidine 1μg/ kg. Group T: TAP block with bupivacaine 0.25% in a dose of (0.5 ml / kg).

NCT ID: NCT06182111 Not yet recruiting - Postoperative Pain Clinical Trials

Intraoperative Administration of Intravenous Morphine in Patients Undergoing Laparoscopic Cholecystectomy

MORPHLAPCHOL
Start date: February 2024
Phase:
Study type: Observational

The goal of this observational, quality improvement study is to compare the effect of a dose of morphine given during gall-bladder removal surgery. The main questions to answer are: - Do participants, who are given given a dose of morphine during gall-bladder removal surgery, experience less pain after surgery? - Does a dose of morphine during gall-bladder removal surgery cause more side effects? The investigators will compare the effects of two types of anesthesia: a) anesthesia without morphine during surgery, and b) anesthesia with morphine during surgery.

NCT ID: NCT06179641 Recruiting - Postoperative Pain Clinical Trials

Comparison of Two Different Regional Analgesia Techniques for Patients Undergoing Total Knee Arthroplasty

PIPACK
Start date: February 8, 2024
Phase: N/A
Study type: Interventional

The objective of this clinical trial is to compare two regional analgesia techniques in patients undergoing total knee arthroplasty: IPACK (Infiltration of local anesthetic between the Popliteal Artery and Capsule of the Knee) vs selective tibial nerve block. The main question is whether one of these peripheral blocks is more effective in reducing postoperative pain than the other. All patients will have a spinal block with an adductor canal block. One group will receive an IPACK block and the other group, a selective tibial nerve block. Postoperative pain scores and morphine consumption, among others, will be compared between groups.

NCT ID: NCT06177665 Recruiting - Postoperative Pain Clinical Trials

Comparison of Erector Spina Plan Block and Rhombodid Intercostal Block in Breast Surgery

Start date: July 1, 2023
Phase: N/A
Study type: Interventional

In this study, the investigators compared ultrasound-guided erector spinae plane (ESP) block and rhomboid intercostal block (RIB) on postoperative analgesic effect in unilateral breast surgery.

NCT ID: NCT06177652 Recruiting - Postoperative Pain Clinical Trials

Postoperative Analgesis for Pain Management After Thoracotomy

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

Thoracotomy is among the most painful surgical procedures and can cause severe pain. Postoperative pain causes many complications. Therefore, pain management is important in patients undergoing thoracotomy. For this purpose, systemic analgesics are used along with ultrasound-guided nerve blocks in thoracotomy pain. The effectiveness of thoracic paravertebral block and serratus plane block in the treatment of post-thoracotomy pain will be evaluated by comparing their effectiveness and complications on postoperative pain. Since the epidural spread of the thoracic paravertebral block is more effective, the effectiveness of postoperative pain relief will be more effective

NCT ID: NCT06166602 Recruiting - Postoperative Pain Clinical Trials

US-guided Pericapsular Nerve Group (PENG) Block in Different Volumes on Postoperative Pain in Hip Replacement Surgeries

Start date: June 20, 2023
Phase: N/A
Study type: Interventional

Postoperative pain management has an important place in anesthesia practices. In order to ensure patient comfort after the surgery, to start postoperative rehabilitation early, and to prevent the process from causing mood disorders such as anxiety and pathological conditions such as chronic pain syndrome, the pain caused by the operation in the postoperative period must be effectively relieved. Pericapsular nerve group (PENG) block; It is a regional anesthesia technique that targets the anterior capsule of the hip joint and aims to block the joint branches of the accessory obturator nerve and femoral nerve by administering local anesthetic. Although it has been described recently, controlled prospective studies in the literature have shown it to be a safe and effective regional technique for postoperative pain after hip surgery. However, volume studies on this block are limited. Therefore, in this study, we aimed to determine the optimal dose by comparing the effectiveness of PENG block on pain using different local anesthetic volumes.

NCT ID: NCT06157762 Not yet recruiting - Postoperative Pain Clinical Trials

Open Technique Erector Spinae Plane Block in Spinal Surgery

Start date: December 2023
Phase: N/A
Study type: Interventional

Erector spinae plane (ESP) block is an interfacial plane block with visceral and somatic analgesic activity at paraspinal muscles.ESPB has been successfully applied as a part of multimodal analgesia in treating postoperative pain in spinal surgery. However, it may be difficult or impossible to perform lumbar ESPB in obese patients or cases of increased lumbar lordosis. This study aims to investigate the effectiveness of ESPB applied by the intraoperative surgeon.

NCT ID: NCT06157645 Not yet recruiting - Postoperative Pain Clinical Trials

Prophylactic Mesh Reinforcement for Stoma Closure

Start date: August 1, 2024
Phase: N/A
Study type: Interventional

n the current work we are aiming to compare between the mesh-reinforced stoma closure and the anatomical closure in terms of the risk of developing surgical site incisional hernia (SSIH),incidence of surgical site infection , post-operative Pain and Hospital stay