Postoperative Ileus Clinical Trial
— pre-TAPIOCAOfficial title:
InteresT And Mechanisms of Percutaneous Posterior tIbial Nerve Stimulation to Prevent pOstoperative Ileus in ColorectAl Surgery: A Preliminary Study
Verified date | October 2017 |
Source | University Hospital, Angers |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Postoperative ileus (POI) causes patient's discomfort and leads to an increase of cost of
management after colorectal surgery because of an increase of the morbidity rate or of the
rate of early rehospitalization after discharge.
Enhanced recovery programs allowed a reduction of its rate but 20 to 30% of patients will
experiment POI.
A new approach during preoperative era, using mastication or preoperative physical activity,
has been proposed to improve postoperative course. This leads to a vagal activation (action
especially on upper GI).
Sacral stimulation using percutaneous tibial nerve stimulation (PTNS) has an effect on lower
GI.
The aim of this study was to assess the efficacy and the feasibility of PTNS during
perioperative course, to prevent POI with respect with placebo.
Status | Completed |
Enrollment | 40 |
Est. completion date | June 9, 2017 |
Est. primary completion date | May 2017 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - patients > 18 years - elective colectomy or proctectomy - agreement for the research Exclusion Criteria: - chronic inflammatory bowel disease - irritable bowel disease documented - history of surgery on oesophagus or stomach - acetylcholine dysfunction - enterostoma - patient holder of pace-maker |
Country | Name | City | State |
---|---|---|---|
France | University Hospital Center | Angers |
Lead Sponsor | Collaborator |
---|---|
University Hospital, Angers |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | delay before solid food tolerance and first stool recovery (expressed in days afters surgery). Day 0 (D0) is the day of surgery. | data collected from 6 hours after the end of surgery to the recovery. This recovery is expected to be between 1 and 6 days after surgery. Recovery will be assessed 3 times a day (7.00 am, 12.00 am, 6.00 pm) |
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT04205058 -
Coffee After Pancreatic Surgery
|
N/A | |
Completed |
NCT02232893 -
Effect of TU-100 in Patients Undergoing Laparoscopic Colectomy
|
Phase 2 | |
Not yet recruiting |
NCT05001763 -
Prucalopride for Postoperative Ileus in Patients Undergoing Robot-assisted Laparoscopic Radical Cystectomy
|
Phase 2 | |
Active, not recruiting |
NCT04547868 -
Can Coffee/Caffeine Improve Post-Operative Gastrointestinal Recovery
|
N/A | |
Completed |
NCT02947269 -
Prucalopride in Postoperative Ileus
|
Phase 3 | |
Recruiting |
NCT05512741 -
Intestinal Microbiota and Postoperative Ileus After Colorectal Surgery
|
||
Recruiting |
NCT04675606 -
Implementing a Low Fiber Diet vs. Regular Diet in Postoperative Colorectal Patients With Ileostomies
|
N/A | |
Completed |
NCT02161367 -
Effect of Simethicone on Postoperative Ileus in Patients Undergoing Colorectal Surgery
|
Phase 4 | |
Completed |
NCT01956643 -
Effect of Sham Feeding on Postoperative Ileus After Elective Liver Transplantation
|
N/A | |
Completed |
NCT00464425 -
Electroacupuncture for Postoperative Ileus After Laparoscopic Colorectal Surgery
|
Phase 3 | |
Completed |
NCT00402961 -
Trial of Acupuncture for Reduction of Post-Colectomy Ileus
|
Phase 2 | |
Terminated |
NCT04100265 -
ANTERO-5: Gastric Motility in Postoperative Ileus
|
N/A | |
Recruiting |
NCT04090073 -
Electroacupuncture Combined With Fast-track Perioperative Program for Laparoscopic Colorectal Surgery
|
N/A | |
Recruiting |
NCT03222557 -
Electroacupuncture for Postoperative Ileus After Laparoscopic Surgery for Mid and Low Rectal Cancer
|
N/A | |
Withdrawn |
NCT02261454 -
RCT Gum Chewing on Bowel Function After Abdominal Surgery in Children
|
N/A | |
Completed |
NCT02639728 -
The Effect of Coffee Consumption in Enhancing Recovery of Bowel Function Following Colorectal Surgery.
|
N/A | |
Completed |
NCT02004652 -
Prucalopride for Postoperative Ileus in Patients Undergoing Gastrointestinal Surgery
|
Phase 2 | |
Completed |
NCT00509327 -
Randomized Clinical Trial of Bisacodyl Versus Placebo on Postoperative Bowel Motility in Elective Colorectal Surgery
|
Phase 4 | |
Completed |
NCT03097900 -
Does Caffeine Enhance Bowel Recovery After Colorectal Surgery?
|
Phase 2 | |
Completed |
NCT03143621 -
The Effect of Coffee After Resection of Small Bowel
|
N/A |