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Pilot Study: Anti-inflammatory Effect of Peroperative Stimulation of the Vagus Nerve

Postoperative Ileus Clinical Trial

Official title:
Pilot Study: Anti-inflammatory Effect of Peroperative Stimulation of the Vagus Nerve: Potential New Therapeutic Intervention to Shorten Postoperative Ileus

Clinical Trial Summary

Hypothesis:

Electrical stimulation of the abdominal vagus nerve has an anti-inflammatory effect and represents a new therapeutic approach to shorten postoperative ileus.

Aims:

In the present pilot study, the investigators want to evaluate the anti-inflammatory effect of peroperative electrical stimulation of the vagus nerve. To this end, the following aims are formulated:

1. to optimize the technique of intra-operative electrical vagus nerve stimulation

2. to show that electrical stimulation of the intra-abdominal vagus nerve reduces the inflammatory response to abdominal surgery

3. to evaluate whether electrical stimulation of the vagus nerve leads to clinical improvement (collect pilot data)

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01572155
Study type Interventional
Source Katholieke Universiteit Leuven
Contact
Status Completed
Phase N/A
Start date March 2012
Completion date December 2015
View Details
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