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Postoperative Delirium clinical trials

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NCT ID: NCT05618236 Active, not recruiting - Clinical trials for Postoperative Delirium

Sugammadex and Neostigmine in Pediatric Patients

Start date: November 8, 2022
Phase:
Study type: Observational [Patient Registry]

In this study, it was aimed to compare the use of sugammadex instead of neostigmine + atropine in the reversal of NMB in children undergoing lower abdominal surgery or urogenital surgery, and to compare the rates of postoperative agitation, nausea and vomiting using the FLACC scale, PAED scale and ICC parameters.After the approval of the local ethics committee and written consent from the family, patients who underwent ASA 1, 5-12 years old lower abdomen surgery or urogenital surgery in Pendik Training and Research Hospital will be included in the study. The patients included in the study will be those who were maintained with routine 2-3% sevoflurane inhalation anesthetic and 0.2mcg/kg/min remifentanil intravenous anesthetic, and decurarized with 0.5-1 mg/kg rocuronium. No drugs other than those administered by the responsible Anesthesiologist during the operation will be administered. The patients included in the study will be divided into 2 groups according to the agent used in decurarization. There is no condition for the number of patients in the group to be equal. Group N; neostigmine+atropine, GROUP S; This will be the group of patients decurarized with sugammadex. 0-45 days after patients are extubated. And at the 2nd hour, FLACC Scale (Pain Diagnostic Scale), PAED (Pediatric Anesthesia Recovery Delirium) Scale assessment methods will be compared in terms of pain and agitation. Nausea and vomiting will be noted as yes/no.

NCT ID: NCT04978870 Active, not recruiting - Cognitive Decline Clinical Trials

Diagnosis, Incidence and Consequences of PACU-Delirium

PADE-DIC
Start date: July 29, 2021
Phase:
Study type: Observational

This study aims to 1. determine sensitivity and specificity of the Confusion Assessment Method for Postanesthesia Care Unit (CAM-PACU) 2. examine the effect of postanesthesia care unit delirium (PACU delirium) on the emergence of later onset postoperative delirium (POD) as well as cognitive recovery until one month postoperatively

NCT ID: NCT03635229 Active, not recruiting - Clinical trials for Postoperative Delirium

Risk Factor of POD and POCD After Cardiac Surgery

Start date: August 21, 2018
Phase:
Study type: Observational

Postoperative delirium (POD) and postoperative cognitive decline (POCD) are common after surgeries in the elderly, especially after cardiothoracic surgery. These conditions are associated with adverse short- and long-term outcomes. Multiple conditions in the perioperative period have been proposed as risk factors of POD and POCD. Incidences vary across institutions due to differences in screening and diagnostic tools.

NCT ID: NCT03629262 Active, not recruiting - Analgesia Clinical Trials

Dexmedetomidine Supplemented Intravenous Analgesia in Elderly After Orthopedic Surgery

Start date: October 28, 2018
Phase: Phase 4
Study type: Interventional

Delirium is common in the elderly after orthopedic surgery and is associated with worse outcomes. The investigators hypothesize that, for elderly patients after orthopedic surgery, dexmedetomidine supplemented intravenous analgesia can reduce the incidence of delirium and improve the long-term outcomes.

NCT ID: NCT03291626 Active, not recruiting - Clinical trials for Postoperative Delirium

Postoperative Delirium: EEG Markers of Sleep and Wakefulness

Start date: October 16, 2018
Phase:
Study type: Observational

Postoperative delirium is a condition in which patients develop temporary difficulties in maintaining attention and thinking clearly. These new problems can appear after surgery and change throughout the day. This confusion can last several days. The overall purpose of this study is to measure brain activity during sleep and wakefulness to learn about their relationships to delirium after surgery. While participants may not feel like their normal self during the study, they are in the best position to help us learn how to improve the recovery of brain function and sleep in others having surgery. The investigators need to learn from those who have and have not become confused after their surgical procedure.