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Effect of Remifentanil on Postoperative Cognition Function in Patients Undergoing Major Abdominal Surgery

Postoperative Confusion Clinical Trial

Official title:
Effect of Remifentanil on Postoperative Cognitive Function in Patients Undergoing Major Abdominal Surgery

Clinical Trial Summary

The purpose of this study is to investigate the effects of two different analgesic methods (Fentanyl vs Remifentanil) during major abdominal surgery on postoperative cognitive status of patients.

Clinical Trial Description

The purpose of this study is to investigate the effects of two different analgesic methods (Fentanyl vs Remifentanil) during major abdominal surgery on postoperative cognitive status of patients. In particular, whether there is a correlation between type of anesthesia and the appearance of postoperative cognitive disorder (POCD), including type of anesthesia and levels of pro and anti inflammatory cytokines and investigate whether there is an association between presence or absence of POCD and cytokines levels ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Screening

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01627873
Study type Interventional
Source Catholic University of the Sacred Heart
Contact
Status Completed
Phase Phase 4
Start date August 2009
Completion date December 2011
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