Postoperative Complication Clinical Trial
Official title:
A Randomized, Double- Blind Multicentric Study of the Effect of Remote Ischemic Preconditioning on Postoperative Complications in Patients Undergoing Major Minimal and Open Visceral Surgery
Remote Ischemic Preconditioning (RIPC) is mediated by intermittent brief episodes (5-10
minutes) of short ischemia in a limb (i.e. arm), followed by reperfusion. For this purpose
in 3-4 cycles, a tourniquet is insufflated to suprasystolic pressure levels for 5 minutes
and deflated for 5 minutes afterwards. The ischemic episodes are known to stimulate
platelets and factors platelet dependent factors such as Serotonin and VEGF. These humoral
factors have a systemic effect and have the potential to protect target organs (i.e. heart,
kidney, liver) remote to the ischemic limb.
The purpose of this randomized controlled study is to investigate the influence and impact
of RIPC on postoperative complications in patients undergoing visceral surgery
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Prevention
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT01141335 -
Polypropylene Mesh Versus Polytetrafluoroethylene (PTFE) Mesh in Inguinal Hernia Repair
|
Phase 4 | |
| Recruiting |
NCT02535039 -
Methylprednisolone Combined Electric-acupuncture on Cognitive Function
|
Phase 1/Phase 2 | |
| Completed |
NCT02445300 -
Efficacy of Wound Care and Reduction of Wound Complications by Use of AQUACEL® Ag Surgical Dressing in MIS TKA
|
Phase 4 | |
| Recruiting |
NCT03205189 -
Comparison Between Pre-operative Prescription Delivered During Anesthesia Consultation or Post-operative Prescription
|
N/A | |
| Recruiting |
NCT01583751 -
Videoendoscopic Pilonidal Sinus Surgery
|
Phase 1 | |
| Recruiting |
NCT02776046 -
Individualized Perioperative Open-lung Ventilatory Strategy With High Versus Conventional Inspiratory Oxygen Fraction (iPROVE-O2).
|
N/A | |
| Not yet recruiting |
NCT02838173 -
Serratus Plane Block for the Prevention of Chronic Pain After Breast Cancer Surgery
|
N/A | |
| Completed |
NCT01883752 -
Goal Directed Fluid Management Based on Non-invasive Monitoring
|
N/A | |
| Completed |
NCT05837793 -
Modified Frailty Index for Minimally Invasive Distal Pancreatectomy
|
||
| Completed |
NCT02696122 -
Quality of Recovery After General or Spinal Anesthesia for Inguinal Hernia Repair
|
N/A | |
| Terminated |
NCT02062788 -
Evaluation of Preoperative Oral Rehydration Solution in Colectomy
|
Phase 3 | |
| Withdrawn |
NCT00789659 -
Incisional Wound Vac in Obese Patients
|
N/A |