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Postoperative Bleeding clinical trials

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NCT ID: NCT06208267 Not yet recruiting - Clinical trials for Postoperative Bleeding

Tranexamic Acid Use on Pain, Mobility and Bleeding Following Total Hip and Total Knee Arthroplasty

TXA
Start date: June 2024
Phase: N/A
Study type: Interventional

Tranexamic acid (TXA) is an anti-fibrinolytic agent developed in the 1960s that has been safely used to reduce blood loss, transfusion rates and bleeding-associated mortality in trauma, obstetrics and orthopedic surgery, including hip fracture care and arthroplasty. The efficacy and safety profile of TXA has been extensively studied in numerous clinical trials and observational studies. Its wide range of applications, combined with its favourable risk-benefit ratio, has led to the incorporation of TXA into clinical guidelines and protocols worldwide. This RCT aims to compare the current standard dosing for TXA to additional TXA doses given orally post-operatively for THA and TKA patients. The goal is to compare the following between study groups: visible bleeding on post-operative dressing, mobilization (steps, amount of time moving around), pain (visual analog scale), function (Oxford hip and knee scales) and ROM at four to six weeks.

NCT ID: NCT06057675 Recruiting - Skin Cancer Face Clinical Trials

Tranexamic Acid in Nasal Mohs Reconstruction

Start date: March 19, 2024
Phase: Phase 2
Study type: Interventional

This study will be a prospective randomized control trial to evaluate the effects of subcutaneously administered TXA among patients undergoing nasal Mohs reconstruction with local flaps at VUMC.

NCT ID: NCT06005831 Completed - Clinical trials for Postoperative Bleeding

Uterine Fundus Pressure in Reduction of Cesarean Bleeding

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Uterine compression methods reduce the amount of postpartum bleeding. In our study, we investigated the effect of fundal pressure, which will be created by a sandbag placed on the abdomen, on reducing post-cesarean bleeding. Material and Methods: A total of 482 patients who delivered by cesarean section (CS) in the Obstetrics Clinic of Fırat University Faculty of Medicine between January 2021 and December 2021 were included in this prospective, randomized, single-center study.

NCT ID: NCT05657327 Active, not recruiting - Pancreatic Fistula Clinical Trials

Application and Optimization of the International Study Group of Pancreatic Surgery (ISGPS) Definition and Grading Criteria for Postoperative Complications of Pancreatic Surgery in Laparoscopic Pancreatic Surgery

Start date: January 1, 2014
Phase:
Study type: Observational

In recent years, with the continuous development of minimally invasive techniques, laparoscopic pancreatic surgery has also been widely used. Although the postoperative mortality rate of laparoscopic pancreatic surgery has been decreasing as the technology continues to improve and mature, the complication rate reported varies widely among centers.The definition and grading criteria of ISGPS on postoperative complications of pancreatic surgery are mostly proposed based on open pancreatic surgery, and most of the data of the later related studies are also for open pancreatic surgery, while the applicability of the definition and grading criteria in laparoscopic pancreatic surgery is still lacking in systematic The study The main purpose of this study is to investigate the applicability of the ISGPS definition and grading criteria for pancreatic fistula, postoperative bleeding and delayed gastric emptying in laparoscopic pancreatic surgery.

NCT ID: NCT05174988 Completed - Clinical trials for Patient Satisfaction

Reducing Postoperative Bleeding After Hysterectomy Via Independent Closure of Vaginal Cuff Angles

Start date: January 31, 2022
Phase: N/A
Study type: Interventional

The investigators propose prospectively evaluating if adding separate sutures to the angles of the vaginal cuff before running barbed suture reduces the incidence of patient's perception of bleeding after surgery.

NCT ID: NCT03515525 Completed - Hematoma Clinical Trials

Analysis of Hematoma Following Breast Surgery

Start date: March 1, 2018
Phase:
Study type: Observational

A retrospective review of patients who developed hematoma following breast surgery from 2003 to 2018 in a single institution was performed. The study investigated the value of closed-suction drains regarding the quantity and quality of fluid secretion for the prediction of subcutaneous hematoma in patients undergoing breast surgery procedures.

NCT ID: NCT01606865 Completed - Clinical trials for Postoperative Bleeding

Platelet Inhibition and Bleeding in Patients Undergoing Non-Cardiac Surgery

BIANCA
Start date: September 2010
Phase: N/A
Study type: Observational

The aim of the study is to evaluate if there is an association between platelet inhibition and surgery-related bleeding in patients undergoing non-cardiac surgery during dual antiplatelet therapy.