Quadratus Lumborum Block Versus Erector Spinae Block in Laparoscopic Cholecystectomy

Postoperative Analgesia Clinical Trial

Official title:

Ultrasound-guided Bilateral Quadratus Lumborum Block Versus Erector Spinae Block for Postoperative Analgesia in Laparoscopic Cholecystectomy

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04689633
• Other study ID #: 135-12/2018
• Status: Completed
• Phase: N/A
• Start date: April 15, 2019
• Est. completion date: January 15, 2020

Study information

• Verified date: December 2018
• Source: Minia University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The patients were randomly allocated into 3 parallel groups of 20 patients in each group by using computer generated tables. group(Q):received bilateral sonar-guided quadratus lumborum bolck using 20 ml bupivacaine 0.25%on each side.group(E): received bilateral ultrasound-guided erector spinae block using 20 ml bupivaciane 0.25%on each side. group(C):didn't received any block

Description:

on arrival to the operative room all patients were monitored with standared monitoring. then IV cannula were inserted. preoxygenation with 100% oxygen and induction of GA by 1mic/kg fentanyl and 2 mg/kg of 1%propofol. endotracheal intubation was facilitated by 0.5mg/kg of atracurium. isoflurane 1-2% with oxygen was used for anesthetic maintenance and 0.15 mg/kg intermittent doses of atracurium to maintain adequate muscle relaxation. ventilation was controlled to maintain end tidal CO2 at 35-40 mmHg and SaO2 between 95-100. after stabilization of the patient's hemodynamics and before surgical incision, quadratus lumborum and erector Spinae block were performed according to patient's group by the same anesthetist with the patient in lateral or prone position respectively.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: January 15, 2020
• Est. primary completion date: December 15, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 70 Years

Eligibility

Inclusion Criteria:

• American society of anesthesiologists(ASA) physical status1and2 scheduled for elective cholecystectomy under general anesthesia

Exclusion Criteria:

• Allergy to studed drugs

• morbid obesity

• patient refusal

• infection at the side of the bolck

• emergency laparoscopic cholecystectomy

• if laparoscopic procedure converted to open

Related Conditions & MeSH terms

• Postoperative Analgesia

Intervention

Procedure:
• nerve block
bilateral ultrasound-guided posterior quadratus lumborum block was done in the lateral decubitus and linear or curvilinear probe was used according to the depth and placed in the midaxillary line in the transverse plane above the iliac crest

Locations

Country	Name	City	State
Egypt	Faculty of Medicine	Minya

Sponsors (1)

Lead Sponsor	Collaborator
Minia University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	time of first postoperative analgesic request	first time that patient need analgesia and visual analogue scale more than 3	24 hours