Stellate Ganglion Block to Reduce Hot Flushes

Status Completed

Clinical Trial Summary

To assess the short-term efficacy of stellate ganglion block on hot flush reduction versus sham procedure

Clinical Trial Description

Hot flushes are the most common symptom of menopause for which postmenopausal (PMP) women seek medical help, in 20% of PMP women hot flushes can persist for up to 15 years.

A possible treatment for hot flushes is stellate ganglion block (SGB), used as a means to interrupt parts of the sympathetic nervous system involved in temperature regulation.

Single centre randomized double blind placebo controlled intervention study Study period of 6 months in which patients will fill out on set time points 5 questionnaires regarding quality of life and keep a diary on hot flush frequency and severity during1 week on the same time points.

Study population:

Postmenopausal women aged 30-70 years old with no other causes of flushing present. Intervention (if applicable) Intervention: Stellate ganglion block versus sham procedure

Follow up with questionnaires during 6 months. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03756272
Study type	Interventional
Source	Rijnstate Hospital
Contact
Status	Completed
Phase	N/A
Start date	September 1, 2017
Completion date	February 1, 2019

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02235051` - Exercise Intervention in Preventing Breast Cancer Recurrence in Postmenopausal Breast Cancer Survivors	N/A
Completed	`NCT01635413` - Group Exercise Training for Functional Improvement After Treatment (The GET FIT Trial)	N/A
Completed	`NCT00701337` - Effect of 17ß-estradiol on Inflammatory-immune Responses in Post-menopausal Women According to Administration Route	Phase 4
Recruiting	`NCT04705623` - Influence of Iyengar Yoga on the Bio-functional Age of Postmenopausal Women	N/A
Withdrawn	`NCT03238703` - Endocrine Therapy in Treating Patients With HER2 Negative, Low Risk Breast Cancer	Phase 4
Recruiting	`NCT03953157` - Dietary and Exercise Interventions in Reducing Side Effects in Patients With Stage I-IIIa Breast Cancer Receiving Aromatase Inhibitors	N/A
Completed	`NCT00338728` - Letrozole and Imatinib Mesylate in Treating Postmenopausal Participants With Estrogen or Progesterone Positive Metastatic Breast Cancer	Phase 2
Completed	`NCT01482702` - Impact of Weight Loss Interventions for Overweight Breast Cancer Survivors	N/A
Not yet recruiting	`NCT05009238` - Effect of l S Exercises on Balance and Spatiotemporal Gait Parameters in P M Women	N/A
Terminated	`NCT01842217` - Validation of [18F]FES for Imaging of Brain Estrogen Receptors	N/A
Completed	`NCT01172574` - Motor Control Exercise in Osteoporotic Women	N/A
Completed	`NCT00530582` - Progesterone Reduces Wakefulness in Sleep EEG and Has no Effect on Cognition in Healthy Postmenopausal Women	Phase 4
Completed	`NCT01825785` - A Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Romosozumab (AMG 785)	Phase 1
Completed	`NCT04364061` - Post Exercise Substrate Oxidation, Appetite and Energy Intakes in Overweight/Obese Postmenopausal Women (EScAPE)	N/A
Completed	`NCT03180294` - Bupropion Hydrochloride in Improving Sexual Desire in Women With Breast or Gynecologic Cancer	Phase 2
Recruiting	`NCT06445842` - Short-term Circuit Training on Muscle Mass and Quality of Life in Sedentary Postmenopausal Women	N/A
Completed	`NCT01753908` - Broccoli Sprout Extract in Treating Patients With Breast Cancer	Early Phase 1
Not yet recruiting	`NCT06377631` - Effect of Multi-ingredient on Visceral Adiposity & Non-alcoholic Fatty Liver Disease in Postmenopausal Women With Abdominal Obesity	N/A
Recruiting	`NCT06228768` - Acupressure for Aromatase Inhibitor-Associated Musculoskeletal Symptoms in Patients With Breast Cancer	N/A
Terminated	`NCT01294397` - Effects of Denosumab on the Pharmacokinetics of Etanercept	Phase 1