Electroacupuncture Therapy for Treating Postherpetic Neuralgia

Status Completed

Clinical Trial Summary

Postherpetic neuralgia (PHN) has a high incidence rate and severely impact on quality of life and health care costs, interfering with physical, emotional and social functioning of affected patients. Current therapeutic options for PHN mainly include analgetic and local anaesthesia for selective nerve blockade. Nevertheless, the efficacy of analgetic is always limited by inevitable side effects, in which patients have poor compliance. Moreover, for some most suffering patients, the control of pain is often unsatisfactory despite the administration of complex combinations. As a non-pharmarceutical therapy, acupuncture is widely use for a wide range of pain conditions. Thus, it might be an alternative treatment for PHN. The aim of this multicenter randomized controlled trial is to investigate the efficacy and safety of electroacupuncture therapy in patients with postherpetic neuralgia.

Clinical Trial Description

This randomized controlled trial will enroll 132 patients with postherpetic neuralgia. All patients will be randomly assigned to either the EA combined with medication group or the medication group via a computerized central randomization system in a 1:1 ratio. Primary outcomes will be change in sensory thresholds and pain intensity. Secondary outcomes will be change in dosage of analgetic, quality of life, anxiety and depression severity and sleep quality. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04594226
Study type	Interventional
Source	The Third Affiliated hospital of Zhejiang Chinese Medical University
Contact
Status	Completed
Phase	N/A
Start date	November 11, 2020
Completion date	December 31, 2021

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04546334` - Erector Spinae Plane Block in Post-herpetic Neuralgia	N/A
Completed	`NCT01688947` - Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Postherpetic Neuralgia (PHN)	Phase 2
Terminated	`NCT01744522` - Leech Therapy for Postherpetic Neuralgia	N/A
Completed	`NCT00478179` - Study of a Bupivacaine Patch (Eladur™) to Treat Post- Herpetic Neuralgia	Phase 2
Completed	`NCT00566904` - New Topical Treatment for Continued Pain After Shingles	Phase 1
Completed	`NCT04099706` - Treatment of Chronic Postherpetic Pain With Autologous Fat Grafting - A RCT	N/A
Terminated	`NCT01603394` - Pilot Study Of Pregabalin And Prediction Of Treatment Response In Patients With Postherpetic Neuralgia	Phase 4
Completed	`NCT01228838` - Study of NGX-1998 for the Treatment of Postherpetic Neuralgia	Phase 2
Completed	`NCT01251211` - Botulinum Toxin in Peripheral Neuropathic Pain	Phase 4
Completed	`NCT00612105` - Safety/Efficacy Study of Retigabine vs. Placebo in Post-Herpetic Neuralgia (PHN)	Phase 2
Recruiting	`NCT04560361` - The Analgesic Effect of Electroacupuncture on Postherpetic Neuralgia	N/A
Recruiting	`NCT05568186` - Correlation Between Thermal Patterns of Infrared Thermal Imaging and Clinical Phenotype in Patients With Postherpetic Neuralgia
Recruiting	`NCT04664530` - The Study on the Esketamine in the Treatment of Postherpetic Neuralgia	Phase 4
Active, not recruiting	`NCT01508676` - Effects of Pennsaid on Clinical Neuropathic Pain	N/A
Completed	`NCT00885586` - Acupuncture in Herpes Zoster Neuralgia (ACUZoster)	Phase 4
Completed	`NCT00576108` - A 2 Week Study of Topical KD7040 in the Treatment of Postherpetic Neuralgia (PHN)	Phase 2
Completed	`NCT00981227` - Efficacy and Safety of Eslicarbazepine Acetate as Therapy for Patients With Post-Herpetic Neuralgia	Phase 2
Completed	`NCT00238511` - An Open-Label Follow-on Trial to Assess the Long-Term Safety and Efficacy of Oral SPM 927 in Subjects With Postherpetic Neuralgia (PHN)	Phase 2
Completed	`NCT00007501` - Shingles Prevention Study	Phase 3
Completed	`NCT05140863` - To Evaluate the Efficacy and Safety of HSK16149 Capsule in Chinese Patients With Postherpetic Neuralgia	Phase 3