Clinical Trial Details
— Status: Recruiting
Administrative data
| NCT number |
NCT00174148 |
| Other study ID # |
9361701250 |
| Secondary ID |
|
| Status |
Recruiting |
| Phase |
Phase 1
|
| First received |
September 13, 2005 |
| Last updated |
December 20, 2005 |
| Start date |
July 2005 |
| Est. completion date |
July 2006 |
Study information
| Verified date |
December 2004 |
| Source |
National Taiwan University Hospital |
| Contact |
Shwu-Fen Wang, PT Phd |
| Phone |
886-2-23123456 |
| Email |
sfwang[@]ntu.edu.tw |
| Is FDA regulated |
No |
| Health authority |
Taiwan: Department of Health |
| Study type |
Observational
|
Clinical Trial Summary
Systematically assessing the proprioception-coordination capacity of the spine in patients
with different severity of neck disability could reveal how the dysfunction of the
sensory-motor system was progressed. From the result of the research, a prospective study
would be designed to test the hypotheses that described the mechanism of neck pain based on
the results to the present study.
Description:
The purposes of this research were to investigate the effect of age and chronic neck pain on
cervical proprioception, the change of ultrasonographic (USD) patterns in deep neck muscle
and superficial neck muscles. The hypotheses of this research included: 1) the alteration of
neck proprioception is determined predominantly by the changed activation deep neck muscles
and superficial neck muscles. 2) Age factor contributes to the alteration of cervicocephalic
sensibility, USD pattern of deep and superficial muscles. 3) Chronic pain contributes to the
alteration of cervicocephalic sensibility, USD pattern of deep and superficial muscles.
Neck proprioception is measured by an ultrasound-based coordinate measuring system (CMS 70P,
Zebris, Germany) by asking the subjects to performed head repositioning to the neutral head
position or to a target position in three cardinal plane. These repositioning error
expressed in root mean square errors could represent the craniocervical kinesthetic
sensibility. The change of muscle thickness (mm) of the superficial (Trapezium, Splenius)
and deep (semispinalis cervicis and multifidus) dorsal neck muscle is measured by a
real-time ultrasonographic scanner (HDI 5000, ATL Ultrasound, USA). Image is obtained for
each cervical level, and the thickness of the muscle is identified manually using a
custom-written C++ computer graphic program. The measurements of pain intensity and pain
frequency are modified from the symptoms questionnaire to indicate the intensity, location,
frequency and duration of pain and disability of the subjects. The age and pain effects for
each independent variables measured in patients with chronic neck pain (pain: intensity,
location, frequency, and duration, NDI), will be tested with the General Linear Model (GLM;
age and pain factors). The confounding factors such as gender, range of motion, body height
and weight are controlled in the regression model.
