EXERT: Exercise Physiology After Thrombosis

Status Recruiting

Clinical Trial Summary

Deep vein thrombosis (DVT) can cause long-term scarring and narrowing of veins. When there is extensive damage to the veins in the legs, groin or abdomen it can affect the way that blood is able to flow back up to the heart. Some patients are left with severe symptoms such as pain, leg swelling and ulcers, and have surgical treatment with nitinol stents to re-open the veins and relieve symptoms. The primary aim of this study is to investigate venous blood flow to the heart during exercise in patients with extensive damage to the veins in the groin and abdomen after DVT, and changes that happen after stenting.

Clinical Trial Description

Participants will have cardiopulmonary exercise testing, 6 minute walk test and basic blood tests to establish exercise tolerance and rule out other heart and lung conditions. Exercise cardiac MRI will be used to evaluate cardiac function during exercise. All participants will complete generic and disease specific quality of life questionnaires. Participants who are having a stenting procedure will repeat assessments 6-8 weeks after surgery. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05296499
Study type	Observational
Source	Guy's and St Thomas' NHS Foundation Trust
Contact
Status	Recruiting
Phase
Start date	September 20, 2019
Completion date	April 20, 2023

View Details

See also
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