Clinical Trials Logo

Clinical Trial Summary

When used in conjunction with a local anesthetic, dexamethasone may prolong both the sensory and motor effects of high supraclavicular brachial plexus nerve block (SBP) in arthroscopic shoulder surgery. This study seeks to determine if there is a relationship between the duration of sensory and motor blockade in supraclavicular brachial plexus nerve blocks (SBP) when combined with increasing doses of dexamethasone.


Clinical Trial Description

The exact mechanism of dexamethasone on peripheral nerve block is unclear. The current theory is that the effect is not dose related, while only 4mg and 8mg doses were studied. Our hypothesis is that the dose differences at 1mg, 2mg, or 4mg, does not have significant effect on the duration of analgesia. Therefore, we are not considering any patients to receive suboptimal dosing of preservative free dexamethasone in this study. ;


Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT01690663
Study type Interventional
Source University of Pennsylvania
Contact
Status Completed
Phase N/A
Start date September 2012
Completion date February 2015

See also
  Status Clinical Trial Phase
Recruiting NCT06275698 - HONEY for the Treatment of POst-Tonsillectomy Pain N/A
Completed NCT05464862 - The Effect of PPB Using 10, 20 and 30 ml of Lidocaine, Study on Volunteers Phase 4
Completed NCT03047434 - Characterization of PostOp Pain in Shoulder and Knee Arthroscopy
Completed NCT03926858 - Patient-reported Outcomes of Postsurgical Pain and Health Related Quality of Life
Terminated NCT03098420 - Dose Escalation of Dexamethasone to Increase Duration of Transversus Abdominal Plane Block Following Cesarean Section Phase 2/Phase 3
Completed NCT03828669 - Recovery Toolkits: Assessment of Pragmatic Behavioral Pain Medicine Delivered In Hospital After Surgery
Completed NCT01911949 - USFIB at the Inguinal Ligament for Total Hip Arthroplasty N/A
Active, not recruiting NCT05838443 - Mindfulness Surgical Pain Outcomes N/A
Recruiting NCT06417528 - Chronic Postsurgical Pain: Multivariate Prediction Model