Determination of the ED50 and ED95 of Prophylactic Norepinephrine Infusion for Preventing Post-induction Hypotension in Elderly Patients Undergoing Major Abdominal Surgery

Norepinephrine Clinical Trial

Official title: Second Affiliated Hosptial， School of Medicine, ZheJiang University

Status Recruiting

Clinical Trial Summary

The goal of this clinical trial is to determine the ED50 and ED95 of prophylactic norepinephrine infusion for preventing post-induction hypotension in elderly patients undergoing major abdominal surgery using up-and-down sequential method . The main question it aims to answer is:

What is the effective concentration of prophylactic norepinephrine infusion for preventing post-induction hypotension in elderly patients.

Participants will receive different concentrations of norepinephrine infusion at the beginning of anesthesia induction until 15 minutes after intubation.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Hypotension
• Post-induction Hypotension

• NCT number: NCT05637164
• Study type: Interventional
• Source: Second Affiliated Hospital, School of Medicine, Zhejiang University
• Contact: Min Yan, Doctor
• Phone: 13757118632
• Email: zryanmin@zju.edu.cn
• Status: Recruiting
• Phase: N/A
• Start date: December 1, 2022
• Completion date: May 30, 2023