Clinical Trials Logo

Clinical Trial Summary

Hypotension after induction of general anesthesia and before surgical stimulation is a prevalent anesthesia-related side effect. The post-induction hypotension disrupts organ perfusion and may cause organ damage particularly acute kidney injury, cerebrovascular stroke, and myocardial ischemia. Post-induction hypotension occurs with greater frequency and severity in the elderly. This is because of aged-related diminished cardiac reserve and impaired autonomic homeostasis. Pleth variability index (PVI) is a software program that measures the dynamic changes of the PI that occurs during a complete respiratory cycle. Our primary outcome is to determine the predictive ability and the optimal cut-off value of pre-anesthesia PVI for predicting elderly patients who are at risk of developing post-induction hypotension


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04886089
Study type Observational
Source Cairo University
Contact
Status Not yet recruiting
Phase
Start date May 2021
Completion date February 2022

See also
  Status Clinical Trial Phase
Recruiting NCT05575661 - Correlation Between Postprandial Hypotension and Post-induction Hypotension in the Elderly.
Completed NCT05671783 - Intraoperative Hypotension and Post-anesthesia Care Unit Recovery
Not yet recruiting NCT05749328 - Effect of Preoperative Oral Carbohydrate on Hypotension After Anesthesia Induction in Elderly Patients With Joint Replacement N/A
Recruiting NCT05881291 - Efficacy and Safety of Ciprofol for General Anaesthesia in Patients Undergoing Transcatheter Aortic Valve Replacement N/A
Not yet recruiting NCT03996213 - Comparison of the Hemodynamic Effect of Three Positions During Induction of Anesthesia N/A
Recruiting NCT05637164 - Determination of the ED50 and ED95 of Prophylactic Norepinephrine Infusion for Preventing Post-induction Hypotension in Elderly Patients Undergoing Major Abdominal Surgery N/A