Continuous Positive Air Way Pressure in Cardiac Rehabilitation After CABG

Post-cardiac Surgery Clinical Trial

Official title:

Effect of Continuous Positive Airway Pressure in Phase 1 Cardiac Rehabilitation After Post CABG

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05044559
• Other study ID #: REC/00593 Memoona Salal
• Status: Completed
• Phase: N/A
• Start date: July 15, 2019
• Est. completion date: February 27, 2020

Study information

• Verified date: September 2021
• Source: Riphah International University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Different studies reported that CPAP is effective to prevent respiratory complication in post CABG patient and have greater impact on walking time, ventilatory function and breathing pattern.

Description:

The walking time (6 minute walk test), effect on arterial blood gasses and long term effects of CPAP on cardiac activity, the previous studies focus only on the acute effects of CPAP along with specific exercises but did not tell about the long term effects. based on these finding this study is design to assess the effectiveness of CPAP in Post-op CABG patients regarding there early mobilization, walking time, ABGs and Ejection Fraction as there prognostic parameters in both phase-1 cardiac rehabilitation within hospital as well as in long-term prognosis, is of great interest.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 38
• Est. completion date: February 27, 2020
• Est. primary completion date: February 27, 2020
• Accepts healthy volunteers: No
• Gender: Male
• Age group: 35 Years to 65 Years

Eligibility

Inclusion Criteria:

• age between 35 to 60 years.

• With a clinical diagnosis of coronary artery disease, underwent elective CABG (Acute)

Exclusion Criteria:

• Low ejection friction (15%)

• Patient those who have any arrhythmias

• Unstable angina

• Patient having pace maker and implantable cardioverter defibrillator

• COPD and asthmatic patient

• Patient having BMI more then 40

Related Conditions & MeSH terms

• Post-cardiac Surgery

Intervention

Other:
• Continuous Positive Air Way Group
CPAP between 10 and 12 cmH2O
• Control Group
Day 1: Bed mobility chest physiotherapy, active assistive ROM 5 repetitions of upper and lower limb, ACBT cycle. ABGS was analyses at first minute of exercise and vital was record after exercise. Day 2: Active range of motion exercise progress with 5 repetitions bed to chair mobility. same exercise progress with 5 repetition and 5 minute walk( day 3rd ).walking time will increase with 10 min at 4 day and at 5th day stair climbing the ABGS was record in ICU 3 days.

Locations

Country	Name	City	State
Pakistan	Northwest General Hospital and research center	Peshawar	KPK

Sponsors (1)

Lead Sponsor	Collaborator
Riphah International University

Country where clinical trial is conducted

Pakistan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Arterial Blood Gasses	measures oxygen and carbon dioxide levels in your blood. It also measures your body's acid-base (pH) level, which is normally balanced when you are healthy.	3 days
Secondary	6 minute walk test	gold standard test to measure exercise capacity and requires less physical space and allows for easier monitoring of vital parameters	3 days
Secondary	Ejection Fraction	expressed as a percentage, of how much blood the left ventricle pumps out with each contraction.	4 week
Secondary	Short Form 12 Questionnaire	measuring tool for mental and physical health components. It consists of 12 questions which cover the eight health domain with one or two question per domain	4 weeks