Post Abdominal Surgery Clinical Trial
Official title:
Comparison of High-Flow Nasal Cannula (HFNC) and Conventional Oxygen Therapy (COT) to Diaphragm Function of Post-Upper Abdominal Surgery Patients
| Verified date | December 2019 |
| Source | Indonesia University |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Interventional |
This study aims to compare diaphragm thickness, air lung distribution, and several clinical and laboratory parameters on post abdominal surgery patients with conventional oxygen therapy vs high-flow nasal cannula
| Status | Completed |
| Enrollment | 66 |
| Est. completion date | December 30, 2019 |
| Est. primary completion date | November 1, 2019 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 18 Years to 65 Years |
| Eligibility |
Inclusion Criteria: - patients from 18 - 65 yrs old, - American Society of Anaesthesia (ASA) status I-III, - BMI < 30, patent airway, - Measurement of Exercise Tolerance before Surgery (METS) Score > 4, - P-POSSUM score <10%, - agreed to the study Exclusion Criteria: - uncooperative subjects, - DNR (do not resuscitate) patients, - patients with tracheostomy, pleural effusion, pneumothorax or pulmonary atelectasis |
| Country | Name | City | State |
|---|---|---|---|
| Indonesia | Cipto Mangunkusumo Hospital | Jakarta Pusat | DKI |
| Lead Sponsor | Collaborator |
|---|---|
| Indonesia University |
Indonesia,
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Ni YN, Luo J, Yu H, Liu D, Liang BM, Yao R, Liang ZA. Can high-flow nasal cannula reduce the rate of reintubation in adult patients after extubation? A meta-analysis. BMC Pulm Med. 2017 Nov 17;17(1):142. doi: 10.1186/s12890-017-0491-6. Review. — View Citation
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Riera J, Pérez P, Cortés J, Roca O, Masclans JR, Rello J. Effect of high-flow nasal cannula and body position on end-expiratory lung volume: a cohort study using electrical impedance tomography. Respir Care. 2013 Apr;58(4):589-96. doi: 10.4187/respcare.02 — View Citation
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* Note: There are 11 references in all — Click here to view all references
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | diaphragm thickness | diaphragm thickness are measured sequentially by abdominal ultrasonography (mm) | 2 months | |
| Secondary | electrical impedance tomography (EIT) data | measured data to assess lung ventilation volume and air distribution | 2 months | |
| Secondary | partial 02 pressure | partial 02 pressure were collected from arterial blood gas analysis (mmHg) | 2 months | |
| Secondary | partial carbondioxyde pressure | partial CO2 pressure were collected from arterial blood gas analysis (mmHg) | 2 months | |
| Secondary | ICON | ICON were measured to observe hemodynamic status | 2 months | |
| Secondary | lactate | lactate were measured from arterial blood | 2 months | |
| Secondary | heart rate | measured from monitor (bpm) | 2 months | |
| Secondary | mean arterial pressure | measured from monitor (mmHg) | 2 months | |
| Secondary | respiratory rate | bpm | 2 months |