PONV Clinical Trial
Official title:
Comparison of Ramosetron Pre-treatment Time for Postoperative Nausea and Vomiting (PONV) and QTc Prolongation
Ramosetron is commonly used to prevent postoperative nausea and vomiting (PONV) in the Eastern Asia. The prolongation of QTc interval is a main side effect. In this study, the pre-treatment time of ramosetron to decrease PONV, and QTc prolongation is compared.
This prospective study evaluate 42 female patients who underwent laparoscopic gynecologic
surgery under general anesthesia. Group I (n=21) receive 0.6mg of ramosetron at anesthesia
induction. Group R (n=21) received the same at the end of surgery. PONV is evaluated at
arrival to post-anesthetic care unit (PACU), before induction, discharge from PACU, 24-, 48-,
and 72- after discharge from PACU. The QTc interval is checked before anesthesia, at arrival
to PACU, and 24-h after discharge from PACU.
Forty two subjects are needed with an α value of 0.05, a power of 0.8, and effect size
difference of 0.9.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT01945502 -
Nasopharyngeal Packing and Rhinologic Surgery.
|
N/A | |
Completed |
NCT01840254 -
Effect of Combination Dexmedetomidine Added to Fentanyl-based Intravenous Patient-controlled Analgesia on Nausea Vomiting in Highly Susceptible Patients Undergoing Lumbar Spinal Surgery: Prospective Double Blinded Randomized Controlled Trial
|
N/A | |
Completed |
NCT00772226 -
The Use of Music as Pain Therapy in Patients Undergoing Laparoscopic Cholecystectomy in a Day Care Unit
|
Phase 3 | |
Completed |
NCT00760253 -
Compare the Side Effects and Difference Awake Level of Three TCI Propofol Formula in TVOR Patients
|
N/A | |
Recruiting |
NCT03783182 -
Betamethasone (Betapred®) as Premedication for Reducing Postoperative Vomiting and Pain After Tonsillectomy
|
Phase 4 | |
Recruiting |
NCT03835234 -
Incidence and Factors Associated With PONV in Regional Anaesthesia
|
||
Recruiting |
NCT04191694 -
Chewing Gum to Prevent Nausea and Vomiting After Caesarean Section Under Spinal Anaesthesia
|
N/A | |
Completed |
NCT02468323 -
Prophylactic Antiemetic Efficacy of Palonosetron Versus Ondansetron for Cesarean Sections Under Regional Anesthesia
|
Phase 4 | |
Recruiting |
NCT05596695 -
Minimisation of Blood Pressure Variability and Postoperative Nausea and Vomiting
|
N/A | |
Recruiting |
NCT04570592 -
Granisetron vs Granisetron and Dexamethasone on the Reduction of Postoperative Nausea and Vomiting
|
Phase 2 | |
Completed |
NCT02116257 -
The Opioid-sparing Effect and Reduced PONV Using Propacetamol in PCA Among Patients With High Risk of PONV
|
N/A | |
Not yet recruiting |
NCT05396716 -
Acupoint Stimulation Alleviates Postoperative Nausea and Vomiting
|
N/A | |
Active, not recruiting |
NCT00892996 -
Efficacy of Prevention for Postoperative Nausea and Vomiting After Intrathecal Morphine in Cesarean Section
|
N/A | |
Recruiting |
NCT04866121 -
Acupuncture for Prevention of Postoperative Nausea and Vomiting
|
N/A | |
Completed |
NCT02809378 -
The Effects of Anesthetic Techniques and Palonosetron Administration on the Incidence of PONV
|
Phase 4 | |
Completed |
NCT05408676 -
Comparison of Dexamethasone Alone vs in Combination With Pericardium 6 (P6) Electrical Stimulation or Granisetron in the Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Breast Cancer Surgery
|
N/A | |
Completed |
NCT01991821 -
European Phase III Study of APD421 in PONV
|
Phase 3 | |
Completed |
NCT00952133 -
Efficacy of IV Palo With IV Dexamethasone vs IV Palo for Prevention of Immediate & Delayed PONV
|
Phase 4 | |
Completed |
NCT04054479 -
Penehyclidine for PONV Prophylaxis After Strabismus Surgery
|
Phase 4 | |
Completed |
NCT05540236 -
Effects of Auricular Acupressure on the Management of Postoperative Nausea and Vomiting After Gynecological Laparoscopic Surgeries
|
N/A |