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Pontine Tumors clinical trials

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NCT ID: NCT06093165 Not yet recruiting - Clinical trials for Diffuse Intrinsic Pontine Glioma

RE-irradiation of Diffuse MIdline Glioma paTients

REMIT
Start date: October 2023
Phase: N/A
Study type: Interventional

The REMIT (RE-irradiation of diffuse MIdline glioma paTients) study evaluates safety and the palliative efficacy of re-irradiation of patients with diffuse midline glioma (DMG). The study will introduce a standard re-irradiation treatment schedule for DMG patients who have progressed following primary treatment.

NCT ID: NCT03352427 Terminated - Glioma Clinical Trials

Study of Dasatinib in Combination With Everolimus for Children and Young Adults With Gliomas Harboring Platelet-Derived Growth Factor Receptor (PDGFR) Alterations

Start date: December 6, 2017
Phase: Phase 2
Study type: Interventional

This trial will evaluate the activity of dasatinib in combination with everolimus for children with gliomas harboring PDGFR alterations, including newly diagnosed high-grade glioma (HGG) or diffuse intrinsic pontine glioma (DIPG) after radiation (stratum A); and recurrent/progressive glioma (grade II-IV, including DIPG) (stratum B).

NCT ID: NCT01058850 Terminated - Brain Cancer Clinical Trials

Phase I Rindopepimut After Conventional Radiation in Children w/ Diffuse Intrinsic Pontine Gliomas

Start date: June 2011
Phase: Phase 1
Study type: Interventional

This is a research study of patients with diffuse intrinsic pontine gliomas. We hope to learn about the safety and efficacy of treating pediatric diffuse intrinsic pontine glioma patients with the EGFRvIII peptide vaccine after conventional radiation.