Dandelion Juice in the Treatment of Dyshidrotic Hand Eczema

Pompholyx Clinical Trial

Official title:

Dandelion Juice in the Treatment of Dyshidrotic Hand Eczema

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00442091
• Other study ID #: 20070010
• Status: Completed
• Phase: N/A
• Start date: December 2010
• Est. completion date: December 2019

Study information

• Verified date: March 2020
• Source: Odense University Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Dandelion juice has been used in herbal medicine for at least 1000 years. Vesicular hand eczema is a rare, but difficult to treat, type of hand eczema. One case report has shown that ingestion of dandelion juice could induce a beneficial effect on this type of eczema. The purpose of this study is to test whether this effect can be retrieved in other patients.

Description:

Dandelion juice has been used in herbal medicine for at least 1000 years. One case report has shown a beneficial effect of this herbal remedy on dyshidrotic hand eczema, and the purpose of this pilot study is to test whether this effect can be retrieved in other patients.

The patients are recruited from our out-patient clinic. Only patients with negative patch tests to Compositae are offered treatment with dandelion juice for 20-30 days.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 4
• Est. completion date: December 2019
• Est. primary completion date: December 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Adult patients with dyshidrotic eczema for at least 1 year and negative patch test reactions to Compositae (tested within the last 3 years) and normal renal and hepatic blood tests.

Exclusion Criteria:

• Treatment with systemic steroids or other immunosuppressive/-modulating drugs, including UV therapy, within the last 3 months.

• Pregnancy, lactation.

• Compositae contact allergy.

• Liver or gall bladder disease.

• Abnormal renal or hepatic blood tests.

Related Conditions & MeSH terms

• Eczema
• Pompholyx
• Vesicular Palmoplantar Eczema

Intervention

Drug:
• dandelion juice
10 ml bid for 20-30 days

Locations

Country	Name	City	State
Denmark	Department of Dermatology, Odense University Hospital	Odense

Sponsors (1)

Lead Sponsor	Collaborator
Odense University Hospital

Country where clinical trial is conducted

Denmark, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Improvement in dyshidrotic hand eczema in the study period assessed by HECSI score.		3-4 weeks
Secondary	Improvement in dyshidrotic eczema in the study period assessed by the patient (Visual Analog Scale).		3-4 weeks