EFficacy of Prophylactic Clip Application in Decrease of Immediate Postpolypectomy Bleeding and Delayed Postpolypectomy Bleeding After Colonoscopic Removal for a Large Pedunculated Polyps

Polyp of Large Intestine Clinical Trial

Official title:

Does a Prophylactic Clip Application Decrease IPPB(Immediate Postpolypectomy Bleeding) and DPPB(Delayed Postpolypectomy Bleeding) After Colonoscopic Removal for a Large Pedunculated Polyps (>1cm)?

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01437631
• Other study ID #: 2011-0653
• Status: Completed
• Phase: N/A
• Start date: September 1, 2011
• Est. completion date: April 30, 2015

Study information

• Verified date: February 2020
• Source: Asan Medical Center
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of this study is to evaluate the efficacy of prophylactic clip application after colonoscopic removal for a large pedunculated polyp (> 1cm) in preventing immediate postpolypectomy bleeding (IPPB) and delayed postpolypectomy bleeding (DPPB).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 137
• Est. completion date: April 30, 2015
• Est. primary completion date: April 30, 2015
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years and older

Eligibility

Inclusion Criteria:

• Patients who have a large pedunculated polyp(>1cm) in the colon

Exclusion Criteria:

• Age under 20 years

• Subjects who are taking anticoagulants

• Subjects who have an abnormal coagulogram (platelet count, international normalized ratio, or activated partial thromboplastin time)

• Subjects who have inflammatory bowel diseases

Related Conditions & MeSH terms

• Hemorrhage
• Polyp of Large Intestine
• Polyps

Intervention

Procedure:
• prophylactic clip application
prophylactic clip application after colonoscopic polypectomy

Locations

Country	Name	City	State
Korea, Republic of	Asan Medical Center	Seoul

Sponsors (1)

Lead Sponsor	Collaborator
Asan Medical Center

Country where clinical trial is conducted

Korea, Republic of, 

References & Publications (1)

Shioji K, Suzuki Y, Kobayashi M, Nakamura A, Azumaya M, Takeuchi M, Baba Y, Honma T, Narisawa R. Prophylactic clip application does not decrease delayed bleeding after colonoscopic polypectomy. Gastrointest Endosc. 2003 May;57(6):691-4. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	the occurrence of immediate post-polypectomy bleeding	At 1 day after endoscopic polypectomy, CBC will be done.	1 day
Primary	the occurrence of delayed post-polypectomy bleeding	At 2 weeks after endoscopic polypectomy, history of hematochezia will be taken at outpatient clinic.	2 weeks