Clinical Trials Logo
  1. Home
  2. Polyp of Colon
  3. NCT04032912

The Non-Optical Resect and Discard Study (NORD) — NORD  

Polyp of Colon Clinical Trial

Official title:
Eliminating the Need for Conventional Histopathological Assessment of Diminutive Colon Polyps - The Non-Optical Resect and Discard Study (NORD)

Clinical Trial Summary

Eliminating the need for conventional histopathological assessment of diminutive colon polyps - The Non-Optical Resect and Discard (NORD) study

Clinical Trial Description

Implementation of this approach by community-based gastroenterologists has failed to reach the required quality benchmarks and studies evaluating optical biopsy have not shown diagnostic test performance results that meet standards set by society guidelines in order to promote its widespread clinical adoption. Optical polyp diagnosis and the current resect and discard approach are too complex for clinical adoption. Thus, clinical implementation of this valuable concept has not been achieved to date and its cost-saving potential has not been realized. In order to effectively operationalize a resect and discard strategy, one must find a different way to distinguish neoplastic from non-neoplastic polyps. There exist differences in the proportion of polyps found to be adenomatous in the left and right colon. One recent study reported that 30% of left-sided polyps and 76% of right-sided polyps were found to be adenomas on histology. Since polyps located in the proximal colon are more likely to be adenomas and polyps in the recto-sigmoid colon are more likely hyperplastic we hypothesized that a model based on polyp location might be able to replace optical biopsy and histopathology. Such an approach would be very simple to adopt by every clinician and would allow for easy adoption into clinical practice. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04032912
Study type Observational
Source Centre hospitalier de l'Université de Montréal (CHUM)
Contact
Status Completed
Phase
Start date May 12, 2017
Completion date May 31, 2019
View Details
See also
  Status Clinical Trial Phase
Completed NCT05178095 - Artificial Intelligence in Colonic Polyp Detection N/A
Completed NCT03179358 - Clinical Trial Verifying C-REX LapAid and C-REX DMH/DMHC N/A
Completed NCT04551014 - Evaluation of EverLift in the Performance of Polypectomy for Polyps 4-9mm N/A
Completed NCT04551001 - Evaluation of Cold Forcep and Cold Snare Polypectomy for Polyps Less Than or Equal to 3mm in Size During Colonoscopy N/A
Completed NCT04378660 - Artificial Intelligence (AI) Validation Study for Polyp Detection N/A
Completed NCT04442607 - Clinical vAliDation of ARTificial Intelligence in POlyp Detection N/A
Completed NCT05499546 - Virtual Scale Function SCALE EYE: Variability and Systematic Differences N/A
Completed NCT04195646 - Computer Aided Detection of Polyps During Colonoscopy Procedures N/A
Completed NCT04899700 - Linked Color Imaging Versus White Light Endoscopy for the Evaluation of Scars of Non-pedunculated Polyps. LCI Scar Study. N/A
Recruiting NCT04500392 - High-flow Nasal Cannula Oxygenation Decrease Hypoxia in Sedated Gastrointestinal Endoscopes in Obesity N/A
Completed NCT04357158 - Breath Analysis as an Additional Test for Colorectal Cancer Screening to Reduce the Number of Unnecessary Colonoscopies N/A
Completed NCT05389397 - De-implementation of Outdated Colonoscopy Surveillance Interval Recommendations Among Patients With Low-risk Adenomas N/A
Recruiting NCT05730192 - EAGLE Trial CADDIE Artificial Intelligence Endoscopy N/A
Completed NCT05829447 - Combining Artificial Intelligence With Balloon Mucosal Exposure Device for Polyp Detection in Screening Individuals N/A
Completed NCT04647266 - Pronostic Score of Morbidity to Determine Risk of Complications After Endoscopic Submucosal Dissection for Colorectal Lesions
Recruiting NCT04117100 - Advanced Endo-therapeutic Procedure : Registry-based Observational Study
Active, not recruiting NCT03089268 - Molecular and Histological Characteristics of Serrated Lesions of the Colon
Completed NCT04924543 - OPtical Diagnosis Training to Improve Dysplasia Characterisation in IBD N/A
Terminated NCT05732233 - RITUAL Ultivision AI CADe Randomized Controlled Trial N/A
Active, not recruiting NCT04889352 - Optimizing Timing of Follow-up Colonoscopy N/A