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Polycystic Ovarian Disease clinical trials

View clinical trials related to Polycystic Ovarian Disease.

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NCT ID: NCT05168865 Withdrawn - Miscarriage Clinical Trials

Letrozole Versus Hormonal Preparation in Frozen Cycles of PCOS Patients.

Start date: August 1, 2023
Phase: Phase 4
Study type: Interventional

One of the indications of freezing is to reduce the risk of ovarian hyperstimulation syndrome particularly in polycystic ovarian disease (PCOS) women. Very few RCTs addressed the issue of optimizing the endometrium for a frozen cycle. Interestingly, Letrozole for ovarian stimulation showed significantly better reproductive outcome when compared with hormone replacement therapy (HRT) cycle. In addition, HRT cycle has been associated with higher miscarriage rate when compared with natural cycle frozen embryo transfer. Nevertheless, there is not yet a well-designed prospective randomized study comparing letrozole and HRT in PCOS women undergoing frozen embryo transfer.

NCT ID: NCT01953146 Completed - Clinical trials for Polycystic Ovarian Disease

The Influence of Polycystic Ovairan Syndrome on Embryonic Developmental Timing

PCOS
Start date: September 2012
Phase: N/A
Study type: Observational

Polycystic ovary syndrome is one of the most common causes of female infertility. The cause of infertility in PCOS is unknown. Factors other than anovulation, including inherited or induced changes in the embryo quality have been suggested. Time-lapse analysis of embryo development is a sensitive method of detecting reduced embryo viability. Yet, there are no data regarding the embryo development in PCOS assessed by time-lapse analysis.