Pneumothorax, Spontaneous Clinical Trial
Official title:
Prospective Study on Clinical Outcomes of Spontaneous Pneumothorax
Pneumothorax can be fatal if treatment is delayed or the pneumothorax is refractory. However, the mortality rates and their risk factors were mainly reported from retrospective studies, and local data regarding the mortality of spontaneous pneumothorax is scarce. This study aims at evaluating the in-hospital mortality and relevant clinical outcomes of spontaneous pneumothorax and identifying their predictive factors. The data collected from this study will also guide the planning of subsequent research to overcome the knowledge and service gap in managing spontaneous pneumothorax.
Status | Recruiting |
Enrollment | 349 |
Est. completion date | September 30, 2026 |
Est. primary completion date | September 30, 2025 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion criteria - All patients with a confirmed diagnosis of spontaneous pneumothorax on admission or during the hospital stay - Age greater than 18 years old - Chinese ethnicity - Able to sign written informed consent to participate in the study Exclusion criteria - Pneumothorax was not found by thoracic imaging - Traumatic pneumothorax (including iatrogenic pneumothorax) - Pneumothorax with recent (within one month) lung resection surgery, that may be due to staple line issues - Trapped lung or non-expandable lungs, without evidence of air leakage - Patients with psychiatric disease or cognitive impairment that may limit their ability of understanding or giving consent to the study |
Country | Name | City | State |
---|---|---|---|
Hong Kong | Prince of Wales Hospital | Hong Kong |
Lead Sponsor | Collaborator |
---|---|
Chinese University of Hong Kong |
Hong Kong,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | To evaluate the in-hospital mortality of spontaneous pneumothorax who admitted to the hospital | To evaluate the in-hospital mortality of spontaneous pneumothorax who admitted to the hospital | 36 months | |
Secondary | To evaluate clinical characteristics and causes of pneumothorax | which include symptomatology, radiographical changes and presence of underlying chronic lung disease (that help ot classify the type of pneumothorax) | 36 months | |
Secondary | To evaluate the risk factors and causes for in-hospital mortality of spontaneous pneumothorax | which include age, body weight, extent of pneumothorax, number of pleural intervention and occurrence of complications | 36 months | |
Secondary | To evaluate other short and long-term outcomes due to pneumothorax | which include Occurrence of respiratory and non-respiratory complications secondary to pneumothorax, 30-day and 90-day mortality rates, length of hospital stay, readmission and recurrence rates | 36 months |
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