Pneumoperitoneum Clinical Trial
Official title:
Insufflation With Carbon Dioxide Reduces Pneumoperitoneum After Percutaneous Endoscopic Gastrostomy (PEG): A Randomized Controlled Trial
The investigators hypothesize that using carbon dioxide for PEG placement versus using room air will decrease post-procedure pneumoperitoneum as well as improve post-procedure bloating/pain, and waist circumference.
Background and study aims: Pneumoperitoneum following PEG placement has been reported in up
to 60% of cases, and while usually benign and self-limited, it can lead to evaluation for
suspected perforation. This study was designed to determine whether using CO2 compared to
ambient air for insufflation during PEG reduces post-procedure pneumoperitoneum.
Patients and Methods: Prospective, double blind, randomized trial of 35 consecutive patients
undergoing PEG at a single academic medical center. Patients were randomized to insufflation
with CO2 or ambient air. Primary outcome was pneumoperitoneum determined by left-lateral
decubitus abdominal x-rays 30 min after PEG placement. Secondary endpoints included
abdominal distention, pain, and bloating.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Prevention
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