Clinical Trials Logo

Pneumonia, Ventilator-Associated clinical trials

View clinical trials related to Pneumonia, Ventilator-Associated.

Filter by:

NCT ID: NCT04242706 Completed - Clinical trials for Ventilator-associated Pneumonia

VITAL - VAP Prevention by BIP (Bactiguard Infection Protection) ETT Evac in Belgian ICUs

VITAL
Start date: October 31, 2018
Phase: Phase 4
Study type: Interventional

The study objective is to determine VAP (Ventilator Associated Pneumonia) baseline incidence in the ICU in patients receiving endotracheal tubes with evacuation lumen with and without Bactiguard coating. The study is randomized, prospective, controlled and blinded. All adult patients hospitalized in the ICUs from two tertiary hospitals (i.e.: Centre Hospitalier Universitaire Sart Tilman Liège , Centre Hospitalier Chrétien de Liège) and considered to be ventilated for more than 24 hours will be eligible to participate in the study.

NCT ID: NCT04233268 Recruiting - COVID19 Clinical Trials

RASCALS: Rapid Assay for Sick Children With Acute Lung Infection Study

RASCALS
Start date: June 6, 2020
Phase:
Study type: Observational

Lower Respiratory Tract infections are a common cause of admission to the intensive care unit. Children routinely receive antibiotics until the tests confirm whether the infection is bacterial or viral. The exclusion of bacterial infection may take 48 hours or longer for culture tests on biological samples to be completed. In many cases, the results may be inconclusive or negative if the patient has already received antibiotics prior to the sample being taken. A rapid assay to detect the most likely cause of infection could improve the speed with which antibiotic therapy is rationalised or curtailed. This study aims to assess whether a new genetic testing kit which can identify the presence of bacteria and viruses within hours rather than days is a feasible tool in improving antibiotic prescribing and rationalisation of therapy in critically ill children with suspected lower respiratory tract infection.

NCT ID: NCT04215692 Recruiting - Fluid Overload Clinical Trials

Lung Ultrasound-guided Fluid Therapy in Pediatric Intensive Care Unit Patients

Start date: November 1, 2019
Phase: N/A
Study type: Interventional

A randomized clinical trial to evaluate the effect of using pulmonary ultrasound to guide fluid therapy on distinct variables.

NCT ID: NCT04208945 Recruiting - Clinical trials for Pneumonia, Ventilator-associated

Nebulized Colistin for Gram Negative VAP Prevention.

VAPICO
Start date: December 2019
Phase: N/A
Study type: Interventional

Colistin is used as an elective treatment of infections of multi drug resistant gram negative bacteria. Until now colistin is used in the therapeutic regimen of these infections intravenous or nebulized. There are a plenty of studies about the efficacy of nebulized colistin in the therapy of pseudomonas aeruginosa pneumonia in patients with cystic fibrosis and in the therapy of ventilator associated pneumonia in ICU. On the other hand there are only a few studies about the use of nebulized colistin in the prevention of ventilator associated pneumonia whereas the role of nebulized colistin in the prevention of severe forms of pneumonia such as VAP due to multi drug resistant gram negative bacteria are limited. This double blinded randomized trial aim to investigate the effect of nebulized colistin on the incidence of patients with due to gram negative bacteria in the ICU compared to nebulized normal saline.

NCT ID: NCT04174274 Not yet recruiting - Clinical trials for The Incidence of Ventilator-associated Pneumonia and Rate of Compliance With Survey Criteria

Investigation of Compliance With Ventilator-Associated Pneumonia Prevention Methods and Incidence of Ventilator-Associated Pneumonia in Intensive Care Units

Start date: December 1, 2019
Phase:
Study type: Observational [Patient Registry]

Ventilator-associated Pneumonia (VAP) is a high-mortality hospital infection that occurs in patients undergoing invasive Mechanical Ventilation (MV) and is frequently encountered in intensive care units. Prolonged mechanical ventilation, prolonged hospitalizations, excessive use of antibiotics and increased medical costs are seen. Therefore, compliance with ventilator-associated pneumonia prevention methods is becoming increasingly important. Therefore, in the investigator's study was to investigate compliance with ventilator-associated pneumonia prevention methods and the incidence of ventilator-associated pneumonia in intensive care units.

NCT ID: NCT04149665 Recruiting - Clinical trials for Mechanical Ventilation Complication

Semirecumbent Position by Mechanical Ventilation

Start date: January 11, 2020
Phase:
Study type: Observational [Patient Registry]

It's based in an observational trial in mechanical ventilated patients. The investigators assess the head of bed elevation angle in the routine treatment of the unit. The investigators decide to assess the time the patient has a semirecumbent position >35°.

NCT ID: NCT04111224 Not yet recruiting - Clinical trials for Ventilator Associated Pneumonia

Evaluation of pentraxin3 as a Marker for Ventilator Associated Pneumonia

Start date: February 1, 2020
Phase:
Study type: Observational

This study will assess the role of pentraxin3 (PTX3) in the early diagnosis of ventilator-associated pneumonia (VAP) and the detection of antibiotic sensitivity for different organisms isolated from tracheal aspirate.

NCT ID: NCT04097899 Completed - Clinical trials for Ventilator Associated Pneumonia

Antimicrobial Stewardship Program and Ventilator Associated Pneumonia

Start date: July 1, 2016
Phase:
Study type: Observational

Antibiotic Stewardship Programs (ASPs) help clinicians improve the quality of patient care and improve patient safety through increased infection cure rates, reduced treatment failures; however, there are different techniques, with variable results, of its application including what is called ASPs bundle and there is a need to investigate the effectiveness of implementing a comprehensive care bundle program including the key components of ASPs and the key items of infection control measures, this program can be called Antimicrobial Stewardship Comprehensive Care Bundle Program (ASCCBP).

NCT ID: NCT04061083 Completed - Clinical trials for Mechanical Ventilation Complication

Effects of Endotracheal Tube Cuff Pressure Control on Microaspiration of Gastric Contents

Start date: May 16, 2019
Phase: N/A
Study type: Interventional

The purpose of study is to determine effects of three different ET cuff pressure control on microaspiration of the stomach contents.

NCT ID: NCT04057625 Not yet recruiting - Clinical trials for Ventilator Associated Pneumonia

Transthoracic Ultrasound in the Diagnosis and Follow-up of Ventilator Associated Pneumonia

Start date: September 2019
Phase: N/A
Study type: Interventional

To evaluate the sensitivity, specificity and diagnostic accuracy of bedside transthoracic ultrasound examination in the diagnosis and follow up of ventilator associated pneumonia.