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Pneumonia, Bacterial clinical trials

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NCT ID: NCT03418272 Withdrawn - Clinical trials for Ventilator Associated Pneumonia

Cultures in PICU Patients Compared to Healthy Children

Start date: February 2023
Phase:
Study type: Observational

This study is being done to determine if the bacteria found in your mouth (oral flora bacteria) in children admitted to the intensive care unit who need to be on a breathing machine is different from the oral flora in healthy children undergoing anesthesia for their dental caries. Children in the intensive care unit with a breathing tube are at a higher risk for getting a lung infection due to the bacteria in the mouth slipping into their lungs past the breathing tube over several days. This means that bacteria are found in the child's lung when this is normally not the case. If the bacteria in the mouth have changed from normal then they may get a pneumonia.

NCT ID: NCT03006679 Withdrawn - Clinical trials for Ventilator-Associated Pneumonia

A Study of Meropenem-Vaborbactam Versus Piperacillin/Tazobactam in Participants With Hospital-Acquired and Ventilator-Associated Bacterial Pneumonia

TANGOIII
Start date: August 2018
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the efficacy, safety, tolerability, and pharmacokinetics (PK) of meropenem-vaborbactam compared to piperacillin/tazobactam for 7 to 14 days in the treatment of hospitalized adults who meet clinical, radiographic, and microbiological criteria for hospital-acquired bacterial pneumonia (HABP) or ventilator-associated bacterial pneumonia (VABP).

NCT ID: NCT02269644 Withdrawn - Clinical trials for Community Acquired Pneumonia

A P3 Comparator Trial in Community Acquired Bacterial Pneumonia

Start date: November 2015
Phase: Phase 3
Study type: Interventional

This study will be a double-blind, randomized, multicenter trial to assess the safety and efficacy of a single 1500 mg IV dose of dalbavancin plus a single 500 mg IV dose of azithromycin in comparison to an approved antibiotic regimen of linezolid 600 mg every 12 hours for 10-14 days plus a single 500 mg IV dose of azithromycin for the treatment of Community Acquired Bacterial Pneumonia.

NCT ID: NCT02218359 Withdrawn - Clinical trials for Pneumonia, Bacterial

Aerosolized Amikacin and Fosfomycin in Mechanically Ventilated Patients With Gram-negative and / or Gram-positive Bacterial Colonization

Start date: October 2014
Phase: Phase 2
Study type: Interventional

To demonstrate the safety and efficacy of adjunctive therapy with the Amikacin Fosfomycin Inhalation System (AFIS) versus aerosolized placebo in mechanically ventilated patients with Gram-negative and / or Gram-positive bacterial colonization.

NCT ID: NCT01666743 Withdrawn - Clinical trials for Community-Acquired Bacterial Pneumonia (CABP)

Safety and Efficacy Study of Ceftaroline in Elderly Subjects With Community-Acquired Bacterial Pneumonia

Start date: November 2012
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine the safety and efficacy of ceftaroline fosamil in elderly subjects with community-acquired bacterial pneumonia (CABP) receiving antibiotic therapy in the hospital.

NCT ID: NCT01602874 Withdrawn - Clinical trials for Complicated Intra-Abdominal Infection

Study Evaluating Tigecycline Versus Ceftriaxone In Complicated Intra-Abdominal Infections & Community Acquired Pneumonia

Start date: January 2011
Phase: Phase 3
Study type: Interventional

The main purpose of this study is to compare the safety of tigecycline versus a ceftriaxone regimen in pediatric subjects (aged 8 to 17 years) with complicated intra-abdominal infections (cIAI) and community acquired pneumonia (CAP).

NCT ID: NCT00914888 Withdrawn - Clinical trials for Complicated Intra-Abdominal Infection

Study Evaluating Tigecycline Versus Ceftriaxone In Complicated Intra-Abdominal Infections & Community Acquired Pneumonia

Start date: January 2011
Phase: Phase 3
Study type: Interventional

The main purpose of this study is to compare the safety of tigecycline versus a ceftriaxone regimen in pediatric subjects (aged 8 to 17 years) with complicated intra-abdominal infections (cIAI) and community acquired pneumonia (CAP).

NCT ID: NCT00645619 Withdrawn - Bacterial Pneumonia Clinical Trials

Use of TREM-1 Protein to Differentiate Viral and Bacterial Pneumonias in Intubated Children

Start date: March 24, 2008
Phase:
Study type: Observational

The purpose of this study is to determine whether a protein called TREM-1 can be used to differentiate viral and bacterial pneumonias in children who are on ventilator support. We propose that the level of TREM-1 will be significantly elevated in the lung fluid of children with bacterial pneumonia and viral with co-existing bacterial pneumonia than in children with pure viral pneumonia.

NCT ID: NCT00245453 Withdrawn - Clinical trials for Pneumonia, Bacterial

Outpatient Registry Trial of Respiratory Tract Infections in Adults

Start date: October 2005
Phase: Phase 4
Study type: Interventional

To measure the speed of bacterial eradication from the respiratory tract after administration of azithromycin or telithromycin.