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Clinical Trial Summary

To evaluate the performance of radiomics in differentiating Pneumocystis jirovecii pneumonia (PCP) from other types of pneumonia and to improve the diagnostic efficacy of non-invasive tests in non-HIV patients.


Clinical Trial Description

Retrospective study, including non-HIV patients hospitalized for suspected PCP from January 2010 to December 2022. The included patients were randomized in a 7:3 ratio into training and validation cohorts. Radiomic features were extracted from semi-automatically identified infected areas in computed tomography (CT) scans and used to construct a radiomic model, which was then compared to a clinical-imaging model built with clinical and semantic CT features in terms of diagnostic performance of PCP. The combination of the radiomic model and serum β-D-glucan levels was also evaluated for PCP diagnosis. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05701631
Study type Observational [Patient Registry]
Source Chinese PLA General Hospital
Contact
Status Active, not recruiting
Phase
Start date January 15, 2023
Completion date June 30, 2023

See also
  Status Clinical Trial Phase
Completed NCT04328688 - Clindamycin-trimethoprim/Sulfamethoxazole for PCP After Solid Organ Transplantation Population.
Recruiting NCT02045160 - A Pharmacokinetic and Pharmacogenetic Study in Patients Receiving Sulfamethoxazole-trimethoprim Therapy N/A