Trial of Simplified Pneumococcal Vaccination in Vietnam II — VPTII  

Pneumococcal Vaccine Clinical Trial

Official title: Trial of Simplified Pneumococcal Vaccination in Vietnam II: The Herd Immunity Approach

Status Completed

Clinical Trial Summary

This is a single-blind, open-label, randomised controlled trial with five groups. There are four different Pneumococcal Conjugate Vaccine (PCV) schedules to be evaluated.

Clinical Trial Description

This is a single-blind, open-label, randomised controlled trial with five groups. There are four different PCV schedules to be evaluated: a 0+1 schedule of PCV10 at 12 months of age (Group V), a 0+1 schedule of PCV13 at 12 months of age (Group W), a 1+1 schedule of PCV10 at 2 and 12 months of age (Group X), and a 1+1 schedule of PCV13 at 2 and 12 months of age (Group Y); along with a control group that receives a dose of PCV10 at 24 months of age (Group Z). Additionally, all participants will receive four doses of Infanrix-hexa at 2, 3, 4 and 18 months of age. ;

Related Conditions & MeSH terms

• Pneumococcal Vaccine

• NCT number: NCT03098628
• Study type: Interventional
• Source: Murdoch Childrens Research Institute
• Status: Completed
• Phase: Phase 2/Phase 3
• Start date: March 8, 2017
• Completion date: June 11, 2020