Escitalopram for Premenstrual Syndrome (PMS) in Teens: A Pilot Study

PMS Clinical Trial

Official title: Escitalopram for Premenstrual Syndrome (PMS) in Teens: A Pilot Study

Status Terminated

Clinical Trial Summary

The purpose of this pilot study is to determine the efficacy and safety of escitalopram administered premenstrually (day 14 through day 2 of the menstrual cycle) for severe PMS in young women ages 15-19 years.

Clinical Trial Description

The medication in this study is a serotonin reuptake inhibitor (SSRI), a class that is considered the first-line treatment for severe PMS at this time. Although data indicate that young women who have PMS in their teen years report the same symptoms and symptom severity as adult women, clinical trials have not included this age group, and there is no information on the efficacy and safety of treatment with a serotonergic antidepressant for PMS in teens. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

• PMS
• Premenstrual Syndrome

• NCT number: NCT00523705
• Study type: Interventional
• Source: University of Pennsylvania
• Status: Terminated
• Phase: Phase 4
• Start date: February 2008
• Completion date: October 2009