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Pleural Mesothelioma Malignant clinical trials

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NCT ID: NCT04177953 Active, not recruiting - Clinical trials for Pleural Mesothelioma Malignant

Nivolumab With Chemotherapy in Pleural Mesothelioma After Surgery

Start date: February 4, 2019
Phase: Phase 2
Study type: Interventional

Patients with malignant pleural mesothelioma stage I-III who have undergone cytoreductive surgery with curative intend consisting of extended pleurectomy / decortication (eP/D) with or without hyperthermic intrathoracic chemoperfusion (HITOC) who will receive a maximum treatment duration of 16 cycles (4 cycles of chemotherapy in both arms + 12 cycles maintenance immunotherapy in treatment arm B). The main objective of the trial is Time-to-next-treatment (TNT), as well as safety and tolerability.