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Impact of Pleural Manometry on Chest Discomfort After Therapeutic Thoracentesis

Pleural Effusion Clinical Trial

Official title:
Manometry- Versus Symptom-Guided Large Volume Thoracentesis: a Randomized Controlled Study

Clinical Trial Summary

This randomized controlled trial attempts to determine whether the measurement of pleural pressures during therapeutic thoracentesis affects the development of chest discomfort after the procedure. During thoracentesis, pleural fluid is drained from the pleural space, resulting in lung expansion. In some cases, the lung is not completely re-expandable, in which case continued drainage results in the development of negative pleural pressures and chest discomfort. Negative pleural pressures may also result in other complications such as re-expansion pulmonary edema and pneumothorax. The identification of negative pleural pressures via manometry during the procedure may lead to a reduction in the complication rate.

Clinical Trial Description

PRIMARY OBJECTIVES:

I. To study the impact of pleural manometry on the development of chest discomfort during therapeutic thoracentesis compared to conventional symptom-guided thoracentesis.

OUTLINE: Patients are randomized to 1 of 2 treatment arms.

ARM I: Patients undergo manometry-guided therapeutic thoracentesis.

ARM II: Patients undergo symptom-guided thoracentesis. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02677883
Study type Interventional
Source Vanderbilt-Ingram Cancer Center
Contact
Status Completed
Phase N/A
Start date January 2016
Completion date March 8, 2019
View Details
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