Effect of Storage Condition on CD47 Expression Level in Platelet Concentrate

Platelet Storage Pool Deficiency Clinical Trial

Official title:

Effect of Storage Condition on CD47 Expression Level in Platelet Concentrate

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05529394
• Other study ID #: Abeer Abdallah Ali
• Status: Not yet recruiting
• Start date: December 20, 2022
• Est. completion date: December 2025

Study information

• Verified date: September 2022
• Source: Assiut University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Effect of storage condition on CD47 expression level in platelet concentrate

Description:

CD47 is a cell surface glycoprotein expressed on all cell types .It is an attractive target for therapy because it is involved in regulation of cell survival and cell death by acting as a ligand for signal-regulatory protein alpha expressed on macrophages

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 1
• Est. completion date: December 2025
• Est. primary completion date: July 2025
• Gender: All
• Age group: 18 Years to 45 Years

Eligibility

Inclusion Criteria:

• donors met AABB criteria

Exclusion Criteria:

• donors not met AABB criteria

Related Conditions & MeSH terms

• Platelet Storage Pool Deficiency

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Assessment of CD47 expression level on platelets by exposure to different storage temperatures	To increase survival time of platelets	3 years