Orthodontics Clinical Trial
Official title:
The Effect of Multiple Injections of Platelets Rich Fibrin (i-PRF) on The Rate of Canine Retraction A Split-mouth: A Randomized Controlled Trial
this clinical trial aims to prove that multiple injections will produce a steady rate of acceleration of orthodontic tooth movement.
Platelet-rich fibrin injection is a second-generation platelet concentrate, prepared from centrifuged blood which is a rich source of platelets, stem cells, and growth factors seven times greater than that released by platelet-rich plasma. It is a simplified procedure with no biochemical manipulation of blood, free from anticoagulants which are known to inhibit wound healing or any gelling agent, and easily usable with a low rate of mistakes during the preparation procedure. A variety of growth factors are released by PRF such as platelet-derived growth factor (PDGF), transforming growth factor β (TGF-β), and vascular endothelial growth factor (VEGF), which play a crucial role in angiogenesis, collagen synthesis, and bone regeneration. Treatment with extraction especially in adult patients may take a longer time due to reported increase in bone density and lower bone regenerative rate. Also, the retraction process to close extraction spaces most of the time is accompanied by bone loss and root resorption as reported in the previous studies. i-PRF can accelerate tooth movement, in addition, prevent tooth retraction undesirable side effects. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Active, not recruiting |
NCT02918240 -
How Often Should We See Our Orthodontic Patients
|
N/A | |
Recruiting |
NCT04105491 -
Patient's Expectations, Preferences, Experiences Before, During and After the Treatment With Invisalign® Aligners
|
||
Active, not recruiting |
NCT03967002 -
Treatment of the Mandibular Dental Crowding With and Without Corticotomy Surgery
|
N/A | |
Completed |
NCT02796911 -
Comparative Study of Different Bone Grafts in Accelerating Tooth Movement
|
N/A | |
Recruiting |
NCT05650359 -
Study of the Use of Orthopulse Photobiomodulation
|
N/A | |
Completed |
NCT03765151 -
The Effectiveness of Low-level Laser Therapy in Orthodontic Retention for Periodontal-compromised Patients
|
N/A | |
Completed |
NCT02901678 -
The Effect of Different Force Magnitudes on Maxillary Posterior Segment Intrusion
|
N/A | |
Not yet recruiting |
NCT01475773 -
Psychological Assessment of Adults Seeking Orthodontic Treatment
|
N/A | |
Completed |
NCT03070444 -
Vacuum-formed Retainer Versus Bonded Retainer to Prevent Relapse After Orthodontic Treatment
|
N/A | |
Enrolling by invitation |
NCT05814991 -
A Cohort Prospective Study of Predictors Influencing the Quality of Visualization of the Operating Field During Orthognathic Surgery
|
||
Completed |
NCT03924726 -
Osseous Evidence Behind Micro-osteoperforation in Accelerating Tooth Movement.
|
N/A | |
Recruiting |
NCT06380790 -
Effect of Laser-aided Csf on the Rate of Leveling and Alignment of Mandibular Anterior Crowding
|
N/A | |
Active, not recruiting |
NCT00871026 -
Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM) - Based Planning and Creation of Orthodontic Appliances
|
N/A | |
Completed |
NCT05562986 -
Impacts of Oral Irrigation in Orthodontic Patients
|
N/A | |
Recruiting |
NCT06167278 -
Indirect Bonding Accuracy of 3D Printed Digital Transfer Trays
|
N/A | |
Completed |
NCT03421886 -
Assessment of the Efficacy of the Aerodentis System
|
N/A | |
Completed |
NCT03714087 -
Occlusal Outcomes by OGS After a Finishing Protocol
|
N/A | |
Withdrawn |
NCT03332082 -
A Commercial Available Tooth Positioner for the Treatment of Simple Orthodontic Relapse
|
N/A | |
Completed |
NCT01246830 -
The Use of 2D and 3D Imaging Modalities and Its Influence on Diagnosis and Treatment Planning in Orthodontics
|
N/A | |
Active, not recruiting |
NCT00871091 -
Study Investigating Tooth Movements With Conventional and Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM) Supported Fixed Appliances
|
N/A |