Clinical Trials Logo
  1. Home
  2. Platelet Aggregation
  3. NCT00763997

Study of the Effect of Dipyrone, Ibuprofen, Paracetamol and Parecoxib on the Platelet Aggregation in Analgetic Dosages

Platelet Aggregation Clinical Trial

Official title:
Study of the Effect of Dipyrone, Ibuprofen, Paracetamol and Parecoxib on the Platelet Aggregation

Clinical Trial Summary

Dipyrone is suggested to inhibit the platelet aggregation comparable to th effect of traditional analgetic substances like Ibuprofen. To verify this hypothesis the investigators conducted the study in comparing patients undergoing traumatologic, visceral or plastic surgical procedures. The investigators randomized them to four groups receiving common analgetic doses of either dipyrone, acetaminophen (paracetamol) or valdecoxib/parecoxib. The investigators took blood samples before initiation of the study drug, 1h, 4hs and 24hs after first intake. The investigators compared the aggregation via aggregometry of platelet rich plasma.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Basic Science

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00763997
Study type Interventional
Source Ruhr University of Bochum
Contact
Status Completed
Phase N/A
Start date February 2004
Completion date December 2004
View Details
See also
  Status Clinical Trial Phase
Completed NCT04492423 - VerifyNow® PRUTest® Cardiovascular Population Expected Values On-Drug Study
Completed NCT03355625 - Platelet Function During Extracorporeal Membrane Oxygenation in Adult Patients
Completed NCT02958657 - Effect of Exercise on Platelet Reactivity After Myocardial Infarction N/A
Completed NCT01815008 - Pharmacogenomics of Antiplatelet Response - I Phase 4
Completed NCT03039205 - Platelet Aggregation in Patients With Coronary Artery Disease and Kidney Dysfunction Taking Clopidogrel or Ticagrelor Phase 2
Completed NCT01557335 - A Study to Evaluate Platlet Aggregation of Clopidogrel, EC Aspirin 81 mg, EC Omeprazole 40 mg Compare to PA32540 Phase 1
Completed NCT05581238 - Validation of a Red Blood Cell Transfusion Prediction Model in a Low Transfusion Rate Population.
Completed NCT00233428 - Study to Determine Racial and Gender Differences in Platelet Aggregation Phase 1
Completed NCT02112539 - Aggreguide A-100 ADP Assay Evaluation N/A
Completed NCT00923988 - Effect of Passive Smoking on Platelet Function and Endothelial Function N/A
Terminated NCT00748371 - Loss of Effect of Aspirin on Platelet Aggregation During Chronic Administration Phase 4
Recruiting NCT05702463 - Assessing Pharmacokinetics and Pharmacodynamics of Daily Enteric-coated Aspirin in Patients With StablE Diabetes II Phase 1
Recruiting NCT04842760 - PLATELET Function Assay With Flow Imaging on ImageSTREAM Cytometer
Withdrawn NCT00942617 - Measurement of Platelet Dense Granule Release in Healthy Volunteers N/A
Recruiting NCT06236243 - Effect of Korean Red Ginseng Extract on Blood Flow in Healthy Adults N/A
Active, not recruiting NCT03615846 - Comparison of the VerifyNow® Aspirin Test and PRUTest® Platelet Reactivity Tests With Investigational Reagent to Reagents Registered in Japan
Completed NCT04369534 - Efficacy and Safety of Individualized P2Y12 Receptor Antagonists Treatment Based on Agregometry Versus Fixed Dose Regimen in Patients After Acute Myocardial Infarction Phase 4
Completed NCT01603966 - Low Dose Aspirin Studied With the AggreGuide N/A
Completed NCT01152229 - Platelet Reactivity In Patients With Nuisance Bleeding On A Thienopyridine N/A
Recruiting NCT03528603 - Acute Assessment of Platelet Reactivity After the Intake of Oleocanthal N/A