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Metagenomic and Metatranscriptomic Analysis of Clinical Plaque Samples

Plaque Clinical Trial

Official title:
Metagenomic and Metatranscriptomic Analysis of Clinical Plaque Samples

Clinical Trial Summary

The objective of this study is to determine the metagenomic and metatranscriptomic analysis of clinical samples.

Clinical Trial Description

This study is a blinded, non-randomized, crossover design. Subjects who meet the inclusion/exclusion criteria will be enrolled in the study. Following enrollment, subjects will be asked to use a washout dentifrice (#200000035883/001/000) for a minimum of 1 week. Fasting plaque will be collected at Baseline and then again at a duplicate baseline collection up to 1 week after the baseline collection. Subjects will be assigned a new dentifrice (#200000035883/001/000) to use for 12 weeks. After 12 weeks' use, fasting plaque will be collected. There will be a duplicate plaque collection up to 1 week after 12 week collection. Subjects will be given a new dentifrice (#200000040228/001/000) to use for the next 24 weeks. After 24 weeks' use, fasting plaque will be collected, and there will be a duplicate plaque collection up to 1 week after this collection. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05138978
Study type Interventional
Source Colgate Palmolive
Contact
Status Completed
Phase Phase 2
Start date October 6, 2017
Completion date October 17, 2018
View Details
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