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Plaque Psoriasis clinical trials

View clinical trials related to Plaque Psoriasis.

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NCT ID: NCT04595409 Completed - Plaque Psoriasis Clinical Trials

A Double-blind Study to Compare the Efficacy, Safety, and Immunogenicity of the Proposed Biosimilar Ustekinumab FYB202 to Stelara® in Patients With Moderate-to-Severe Plaque Psoriasis

VESPUCCI
Start date: November 9, 2020
Phase: Phase 3
Study type: Interventional

This is a randomized, double-blind, multicenter study to evaluate the efficacy, safety, and immunogenicity of FYB202 compared to Stelara® in patients with Moderate-to-Severe Plaque Psoriasis.

NCT ID: NCT04594928 Completed - Plaque Psoriasis Clinical Trials

A Study Evaluating the Effects of GLPG3667 Given as an Oral Treatment for 4 Weeks in Adults With Moderate to Severe Plaque Psoriasis

Start date: October 19, 2020
Phase: Phase 1
Study type: Interventional

The purpose of this research study is to assess the safety, tolerability, efficacy, pharmacokinetics and pharmacodynamics of GLPG3667 in multiple daily oral doses in subjects with moderate to severe plaque psoriasis.

NCT ID: NCT04453137 Completed - Plaque Psoriasis Clinical Trials

Pharmacokinetic, Efficacy, Safety, and Immunogenicity of AVT02 With Moderate to Severe Chronic Plaque Psoriasis

Start date: June 30, 2020
Phase: Phase 3
Study type: Interventional

Pharmacokinetic, Efficacy, Safety, and Immunogenicity Between Patients with Moderate to Severe Chronic Plaque Psoriasis Receiving Humira® and Patients with Moderate to Severe Chronic Plaque Psoriasis

NCT ID: NCT04428411 Completed - Plaque Psoriasis Clinical Trials

Study To Evaluate The Impact Of Difficult To Treat Sites On Biological Response In Moderate-To-Severe Plaque Psoriasis(PsO).

Start date: July 5, 2020
Phase:
Study type: Observational

This study is to evaluate available local data in Iraq patients with moderate-to-severe plaque psoriasis on Enbrel treatment with regards to efficacy, treatment for PsO who have difficult to treat sites at presentation.

NCT ID: NCT04398732 Completed - Plaque Psoriasis Clinical Trials

Study to Evaluate the Efficacy of Enbrel as a Biological Treatment in Moderate to Severe Plaque Psoriasis Patients

Start date: July 5, 2020
Phase:
Study type: Observational

This study is to evaluate available local data in Iraqi patients with moderate to severe psoriasis on Enbrel treatment with regards to efficacy, treatment regimen adherence and patient characterization (i.e. age, gender, smoking status) using data from the Dermatologists in Baghdad Teaching Hospital registry

NCT ID: NCT04279119 Completed - Plaque Psoriasis Clinical Trials

Maximal Usage Pharmacokinetics and Safety of ARQ-151 in Adolescents and Adults With Chronic Plaque Psoriasis

MUSE
Start date: March 10, 2020
Phase: Phase 1
Study type: Interventional

This is a phase 1, open label, single arm study in which ARQ-151 cream 0.3% is applied QD for 2 weeks to adolescent subjects with chronic plaque psoriasis involving at least 10% body surface area (BSA) and adult subjects with chronic plaque psoriasis involving at least 20% BSA (excluding scalp). The objectives of this study are to evaluate the exposure and characterize the plasma pharmacokinetic profile and to assess the safety and tolerability of ARQ-151 cream 0.3% administered once daily for 2 weeks to adolescent and adult subjects with chronic plaque psoriasis.

NCT ID: NCT04263610 Completed - Plaque Psoriasis Clinical Trials

Efficacy and Safety of Tildrakizumab in Participants With Moderate-to-Severe Chronic Plaque Psoriasis Who Are Non-Responders to Dimethyl Fumarate Therapy

TRANSITION
Start date: September 4, 2019
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess the efficacy, safety and tolerability of Tildrakizumab in moderate-to-severe plaque psoriasis participants who are non-responder to Dimethyl fumarate (DMF) at Week 16. The study consists of two parts. Part 1 will include the first 16 weeks of the Treatment Period and Part 2 will include the last 24 weeks of the Treatment Period.

NCT ID: NCT04229836 Completed - Plaque Psoriasis Clinical Trials

Efficacy and Safety of Tildrakizumab 100 Milligrams (mg) in Participants With Moderate-Severe Chronic Plaque Psoriasis and Its Impact on Their Quality of Life (TRIBUTE)

TRIBUTE
Start date: December 17, 2019
Phase: Phase 4
Study type: Interventional

The main aim of the study is to evaluate the efficacy, safety and impact on the health-related quality of life (HRQoL) in participants with moderate-to-severe chronic plaque psoriasis who are treated with tildrakizumab 100 milligrams (mg).

NCT ID: NCT04203433 Completed - Plaque Psoriasis Clinical Trials

A Study of DLX105-DMP in Subjects With Plaque Psoriasis

Start date: March 21, 2022
Phase: Phase 1
Study type: Interventional

A Pilot, Open-Label Study in Subjects with Mild-to-Moderate Plaque Psoriasis to Investigate the Safety, Tolerability, and Preliminary Efficacy of a Four-Week Multidose Regimen of DLX105-DMP Administered to a Target Lesion

NCT ID: NCT04173637 Completed - Plaque Psoriasis Clinical Trials

Clinical Study of AK101 in Subjects With Moderate to Severe Plaque Psoriasis

Start date: December 19, 2019
Phase: Phase 2
Study type: Interventional

This is a multiple-center, randomized, double-blind, placebo-controlled Phase IIb study to evaluate the efficacy and safety of AK101, an anti-IL-12/23 p40 antibody, when administered subcutaneously, in subjects with moderate-to-severe plaque psoriasis. The study will consist of 3 periods: up to 4 weeks screening, 12 weeks double-blinded treatment and long-term follow-up period(up to 52 weeks).