Platelet Rich Plasma in Plantar Fasciitis

Plantar Fascitis Clinical Trial

— PRP  

Official title:

Musculoskeletal Ultrasound Changes in the Plantar Fascia After a Single Injection of Platelet Rich Plasma Compared to Steroid

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05339542
• Other study ID #: Rheumatology Dep.
• Status: Completed
• Phase: N/A
• Start date: March 10, 2022
• Est. completion date: July 2, 2022

Study information

• Verified date: July 2022
• Source: Minia University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

a number of patient diagnosed as degenerative plantar fasciitis will be collected and divided into two groups, group I will be injected by platelet rich plasma and group II will be injected methylprednisolone

Description:

the study will include 100 patients diagnosed as degenerative plantar fasciitis and will be evaluated by musculoskeletal ultrasound by two observes and the will divided randomly into two groups who will be injected under ultrasound imaging by either Platelet rich plasma or methylprednisolone. selection of patient will be randomly and the study will be double blinded.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 98
• Est. completion date: July 2, 2022
• Est. primary completion date: July 1, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Clinical diagnosis of plantar fasciitis

Exclusion Criteria (history or current):

• Rheumatic diseases
• Foot Trauma
• Neurological diseases
• Thyroid disease
• Diabetes mellitus
• Chronic Renal Failure

Related Conditions & MeSH terms

• Fasciitis
• Fasciitis, Plantar
• Plantar Fascitis

Intervention

Other:
• platelet rich plasma
derived from patient own blood

Drug:
• MethylPREDNISolone 40 MG
active comparative intervention

Locations

Country	Name	City	State
Egypt	Minya university	Minya

Sponsors (1)

Lead Sponsor	Collaborator
Minia University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	visual analogue scale	visual analogue scale from 0-10, where 0 denoting maximum pain relief and 10 denoting no pain relief	3 months
Primary	Manchester-Oxford Foot Questionnaire	the Manchester-Oxford Foot Questionnaire is a 16-item instrument answered on a five-point Likert scale (each item is scored from 0 to 4, with 4 denoting 'most severe'). Scores for each item are summed to form three separate sub scales representing underlying domains: walking/standing problems (seven items), foot pain (five items), and issues related to social interaction (four items)	3 months
Secondary	echogenicity in longitudinal scan gray scale ultrasound	Hypoechogenicity was defined as a lack of the homogeneous fibrillar pattern with loss of the tightly packed echogenic lines after correcting for anisotropy. increased echogenicity is consistent with plantar fasciitis	3 months
Secondary	plantar fascia thickness at the insertion in longitudinal scan of the heel	measurement of plantar fascia thickness at the insertion in longitudinal view of the heel. Normal thickness is = 4mm. increased thickness is consistent with plantar fasciitis	3 months