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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT05337527
Other study ID # uFrancisco_Vitoria_
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date March 1, 2022
Est. completion date April 10, 2022

Study information

Verified date May 2022
Source Universidad Francisco de Vitoria
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Beetroot juice supplementation has shown the capacity for provoking different physiological effects (e.g. vasodilation and muscle contraction increments). However, the effects of beetroot juice ingestion on neuromuscular performance in women older adults are barely studied. In this randomized placebo-controlled study, we investigated the effects of beetroot acute supplementation in improving neuromuscular performance in women older adults


Description:

Beetroot juice supplementation has shown the capacity for provoking different physiological effects that could affect human performance (e.g. vasodilation and muscle contraction increments). Although this dietary supplement has been commonly used for improving sports performance in recreational or professional athletes, the scientific literature in older adults is scarce. Thus, in our knowledge, no previous studies have analyzed the side effects associated to ingestion in this population group. In this randomized placebo-controlled study, we investigated the effects of beetroot acute supplementation in improving neuromuscular performance and side effects associated with ingestion in women older adults.


Recruitment information / eligibility

Status Completed
Enrollment 9
Est. completion date April 10, 2022
Est. primary completion date March 18, 2022
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Female
Age group 65 Years to 80 Years
Eligibility Inclusion Criteria: - Women >65 or <85 years of age. - In good health, as determined by the investigator's review of history. Exclusion Criteria: (based in previous studies on this topic (doi: 10.1093/gerona/glaa311). Men and women <65 or >85 years of age Unable to provide informed consent Current smokers Significant orthopedic limitations or other contraindications to strenuous exercise Those taking proton pump inhibitors, antacids, xanthine oxidase inhibitors, or on hormone replacement therapy Those taking anti-coagulants or on anti-platelet therapy History of neuromuscular disease (e.g., cervical spondylotic radiculomyelpathy, lumbar spondylosis, amyotrophic lateral sclerosis, Guillain-Barré syndrome, and acquired demyelinating polyneuropathies) Cardiovascular disease (e.g., > stage I hypertension, heart failure, myocardial infarction/ischemia significant myocardial or pericardial diseases (e.g. amyloidosis, constriction), Moderate or severe valvular disease, renal disease, liver disease, or anemia

Study Design


Related Conditions & MeSH terms


Intervention

Dietary Supplement:
beetroot juice
Acute effects of beetroot juice or placebo juice ingestion

Locations

Country Name City State
Spain Universidad Francisco de Vitoria Pozuelo de Alarcón Madrid

Sponsors (1)

Lead Sponsor Collaborator
Universidad Francisco de Vitoria

Country where clinical trial is conducted

Spain, 

Outcome

Type Measure Description Time frame Safety issue
Primary Changes in maximal isometric handgrip strength (N) Using a dynamometer and measuring dominant/ non-dominant side 1-week
Primary Changes in 6-m gait speed test Using a photocell timing gates (seconds) 1-week
Primary Changes in Time Up and Go test Using a photocell timing gates (seconds) 1-week
Primary Changes in Sit and Stand Test Using Power Frail APP 1-week
Primary 6-Minute Walk Test 1-week
Secondary Rate of perception effort (RPE) Using a validated scale (1-10 points) 1-week
Secondary Side effects questionnarie Using a side-effects questionnarie (YES/NO scale) 1-week
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