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Clinical Trial Summary

The purpose of this study is to evaluate the safety and effectiveness of Deucravacitinib (BMS-986165) in Pityriasis Rubra Pilaris as assessed by the change in Investigator Global Assessment (IGA), PASI- 50, 75, 90, DLQI, NRS itch, and Skindex-16 at week 24. To predict responses through the identification of unique biomarkers of PRP utilizing single-cell RNA sequencing.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06444399
Study type Interventional
Source Mayo Clinic
Contact Aaron Mangold, MD
Phone (480) 301-8000
Email mangold.aaron@mayo.edu
Status Not yet recruiting
Phase Phase 2
Start date July 1, 2024
Completion date July 1, 2025

See also
  Status Clinical Trial Phase
Completed NCT03975153 - Guselkumab in the Treatment of Pityriasis Rubra Pilaris (PRP) Phase 2
Completed NCT03485976 - Ixekizumab in the Treatment of Pityriasis Rubra Pilaris (PRP) Phase 2
Terminated NCT00815633 - A Pilot Study of Alefacept for the Treatment of Pityriasis Rubra Pilaris Phase 4
Completed NCT03342573 - Cosentyx (Secukinumab) for the Treatment of Adult Onset Pityriasis Rubra Pilaris Phase 1