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Pituitary clinical trials

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NCT ID: NCT05601141 Active, not recruiting - Pituitary Clinical Trials

Clinics and Epidemiology of Pituitary Diseases in Modena Area Population

DataPit
Start date: October 24, 2022
Phase:
Study type: Observational [Patient Registry]

This is an observational, longitudinal, single-center study. The study is divided in two phases: - FIRST PHASE (retrospective): registration of all patients affected by pituitary disorders followed at the Unit of Endocrinology of Azienda Ospedaliero-Universitaria of Modena - SECOND PHASE (prospective): enrollment of all patients affected by pituitary disorders who attend the Unit of Endocrinology of the Azienda Ospedaliero-Universitaria of Modena. An anonymized database will be created to collect the data of the patients. In particular, the data collected for each patient will include: personal data, data relating to pituitary pathology, symptoms at diagnosis, physical examination, radiological imaging, visual field data, data on surgical intervention, data on histological examination, biohumoral examinations, hormone tests, densitometric data, data on replacement therapies, medical therapies or other pharmacological therapies, data on comorbidities.

NCT ID: NCT04042753 Active, not recruiting - Pituitary Tumor Clinical Trials

Nivolumab and Ipilimumab in People With Aggressive Pituitary Tumors

Start date: July 31, 2019
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if nivolumab and ipilimumab are effective treatment for people with pituitary tumors have gotten worse after surgery and radiation.

NCT ID: NCT03636568 Active, not recruiting - Surgery Clinical Trials

Hyponatremia Study (Delayed Hyponatremia After Pituitary Surgery)

DHAPS
Start date: June 2, 2016
Phase: N/A
Study type: Interventional

Hyponatremia is defined as sodium below the normal range of 135-145. Symptomatically, it can cause patients to experience a wide range of symptoms including lethargy, headache, nausea, vomiting and in severe cases coma and even death. The goal of this study is to prospectively compare two approaches to the postoperative fluid management of patients undergoing transsphenoidal resection of a pituitary tumor or cyst to decrease the occurrence of postoperative delayed hyponatremia. One group will be placed on moderate fluid restriction and the other group will be placed on ad lib fluid intake.