Detection of Functioning Pituitary Microadenoma: PET/MRI Versus PET/CT

Status Recruiting

Clinical Trial Summary

This is a prospective case-control study to compare the usefulness of 18F-FDG PET/MRI with that of 18F-FDG PET/CT in detection of functioning pituitary microadenomas.A single dose of 370 Mega-Becquerel (MBq) 18F-FDG will be injected intravenously.Visual and semiquantitative method will be used to assess the PET/MRI and PET/CT images.

Clinical Trial Description

Magnetic resonance imaging (MRI) may be insufficient to locate functioning pituitary microadenoma.This study compared the usefulness of 18F-FDG PET/MRI with that of 18F-FDG PET/CT in detection of functioning pituitary microadenomas in patients with inconclusive conventional MRI findings. Trans-sphenoidal adenomectomy was performed within 2 weeks of imaging.The PET/CT and PET/MRI findings and tracer uptake levels were correlated with the surgical findings and pathological results. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03404414
Study type	Interventional
Source	Peking Union Medical College Hospital
Contact	Hao Wang, PhD
Phone	+86 10 69154196
Email	474556259@qq.com
Status	Recruiting
Phase	Phase 1
Start date	February 2013
Completion date	November 2018

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