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Clinical Trial Summary

This study will be conducted to investigate the incidence of caries in pits and fissures sealed with a bioactive sealant compared to a fluoride releasing resin based pits and fissures sealant in preventive treatment procedures in adult population over a six months period.


Clinical Trial Description

The study will be conducted in Conservative Dentistry Department, Faculty of Dentistry, Cairo University, The operator in charge will be: Mohamed Tarek Heiba. The researcher will bear ultimate responsibility for all activities associated with the conduct of a research project including recruitment of patients, explaining and performing the procedures to them,A total of 40 volunteer patients with at least 2 non-cavitated molar teeth will be assigned in this study. Patients will be randomly divided into two groups according to type of sealant (S) where in group S1, pits and fissures will be sealed with bioactive pits-and-fissure sealant; while group S2, pits and fissures will be sealed with fluoride releasing resin based pits and fissures sealant. Each restoration will be assessed after three, six months,The tooth will be illuminated with a violet light approximately 405 nm thus stimulating both prophyrins to emit red light that contains less energy. the denser the bacteria colonization on tooth's surface, the more intense the red fluorescent signal; in contrast sound enamel sent out a green fluorescent signal. These light signals are recorded by the highly developed optics and analyzed by the device's software. The software filters and quantifies the fluorescence emitted by the dental tissue and converts the relationship between green and red. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03628729
Study type Interventional
Source Cairo University
Contact mohamed heiba
Phone 01000568165
Email m.tarek.heiba@gmail.com
Status Not yet recruiting
Phase N/A
Start date August 2018
Completion date January 2019

See also
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Not yet recruiting NCT04929327 - Retention Rate of Self-etch Resin Based Sealant With and Without Prior Sandblasting N/A
Completed NCT05146479 - Effectiveness of Sealants and Fluoride Varnish in Caries Prevention in Children With Autism Spectrum Disorders
Enrolling by invitation NCT04163354 - Glass Ionomer Sealant Versus Fluoride Varnish on Occlusal Caries Prevention N/A